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Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders. ....

Yi Xiao Sean Jiang , Pauld Boyer , Michael Sawaya , David Eisenberg , Qin Cao , Emily Henderson , University Of California Los Angeles , Howard Hughes Medical Institute , Mayo Clinic , Molecular Biology , Molecular Biology , Neurodegenerative Disorder , Tdp 43 ,