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NIH Distributes $185M for Impact of Genomic Variation on Function (IGVF) Consortium

NIH Distributes $185M for Impact of Genomic Variation on Function (IGVF) Consortium
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UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells
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Genetic Tools Detect Culprit for Type 1 Diabetes

Genetic Tools Detect Culprit for Type 1 Diabetes
by Angela Mohan on
May 21, 2021 at 10:28 AM
Nature.
Type 1 diabetes is am autoimmune disease with loss of insulin-producing pancreatic beta cells. It is less common than type 2 diabetes, but its prevalence is growing. Currently, there is no cure, only disease management.
The U.S. Centers for Disease Control and Prevention projects 5 million Americans will have type 1 diabetes by 2050.
Numerous genome-wide association studies (GWAS) have been conducted in recent years in which researchers compare whole genomes of persons with the same disease or condition, searching for differences in the genetic code that may be associated with that disease or condition. ....

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GWAS and Single-Cell Epigenomics Provide Insights Into Type 1 Diabetes

By mapping its genetic underpinnings, researchers have identified a predictive causal role for specific cell types in type 1 diabetes. ....

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Genetic tools help identify a cellular culprit for type 1 diabetes

Genetic tools help identify a cellular culprit for type 1 diabetes
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