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"Nicotinic acetylcholine receptor subtype expression, function, and pha" by Han Shen Tae and David J. Adams

The pentameric nicotinic acetylcholine receptors (nAChRs) are typically classed as muscle- or neuronal-type, however, the latter has also been reported in non-neuronal cells. Given their broad distribution, nAChRs mediate numerous physiological and pathological processes including synaptic transmission, presynaptic modulation of transmitter release, neuropathic pain, inflammation, and cancer. There are 17 different nAChR subunits and combinations of these subunits produce subtypes with diverse pharmacological properties. The expression and role of some nAChR subtypes have been extensively deciphered with the aid of knock-out models. Many nAChR subtypes expressed in heterologous systems are selectively targeted by the disulfide-rich α-conotoxins. α-Conotoxins are small peptides isolated from the venom of cone snails, and a number of them have potential pharmaceutical value. ....

Cone Snail , Nicotinic Acetylcholine Receptor ,

Biosynth Further Strengthens Peptide Business with Acquisition of Cambridge Research Biochemicals.

Addition of UK based peptide and antibody production facilities expands peptides and biologics business in UK and Europe. Biosynth, a supplier of critical raw materials to the life science industry ....

United Kingdom , Aimee Cossins , Emily Humphrys , Urs Spitz , Cambridge Research Biochemicals , Managing Director , Cambridge Research , Complex Chemicals , Key Biologics , Ampersand Capital Partners , Research Biochemicals , Gefallene Big Techs ,

Bicycle Therapeutics Announces Collaboration With the German Cancer Research Center, to Discover and Develop Wholly Owned Bicycle® Radio Conjugates for a Range of Oncology Targets

Bicycle Therapeutics plc , a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide technology, today announced that it has entered. | May 4, 2023 ....

United Kingdom , Baden Wüberg , Matthias Eder , Kevin Lee , German Cancer Research Center Deutsches Krebsforschungszentrum , German Cancer Research Center , University Of Heidelberg , Cancer Information Service , Bicycle Therapeutics , Cancer Research , Chief Executive Officer , Bicycle Toxin Conjugates , Bicycle Toxin Conjugate , Cancer Research United Kingdom Centre , Deutsches Krebsforschungszentrum , Information Service , Bicycle Therapeutics Plc Stock Exchange , Press Release , As Bcyc Us0887861088 ,

BOC Sciences Unveils Comprehensive Capabilities of Custom Peptide Drug Conjugate

BOC Sciences Unveils Comprehensive Capabilities of Custom Peptide Drug Conjugate ....

New York , United States , Company Website , Boc Sciences , United States April , Google News , Icrowd News Wire , Comprehensive Capabilities , Boc Sciences , Nveils Comprehensive , Custom Peptide ,

MyJournals.org - Science - 'Molecules, Vol. 28, Pages 3661: The Antimicrobial Peptide γ-Thionin from Habanero Chile (Capsicum chinense) Induces Caspase-Independent Apoptosis on Human K562 Chronic Myeloid Leukemia Cells and Regulates Epigenetic Marks' (Molecules)

MyJournals.org - Science - Molecules, Vol. 28, Pages 3661: The Antimicrobial Peptide γ-Thionin from Habanero Chile (Capsicum chinense) Induces Caspase-Independent Apoptosis on Human K562 Chronic Myeloid Leukemia Cells and Regulates Epigenetic Marks (Molecules) ....

Amma Thionin , Hinense , Aspase Independent ,