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Ibrutinib Plus Venetoclax With MRD-Directed Duration of Treatment Is a New Standard-of-Care Regimen for Previously Unmanaged CLL - Vimarsana News

Ibrutinib Plus Venetoclax With MRD-Directed Duration of Treatment Is a New Standard-of-Care Regimen for Previously Unmanaged CLL

The MRD-guided treatment approach has a significant advantage over chemotherapy.

Personalized treatment for leukemia results in longer life and fewer side effects - Vimarsana News

Personalized treatment for leukemia results in longer life and fewer side effects

Personalized treatment for the most common form of adult leukemia helps patients survive for longer and stay in remission, a phase III trial has found.

Measurable Residual Disease-Guided Therapy Promising in CLL - Vimarsana News

Measurable Residual Disease-Guided Therapy Promising in CLL

The ibrutinib-venetoclax combination was particularly effective in patients with chronic lymphocytic leukemia with high-risk features such as IGHV unmutated disease or chromosomal abnormalities.

'New Gold Standard' for Previously Untreated CLL - Vimarsana News

'New Gold Standard' for Previously Untreated CLL

Personalized, time-limited regimen of venetoclax plus ibrutinib improves survival versus FCR

Ibrutinib Plus Venetoclax With MRD-Directed Duration of Treatment Is a New Standard of Care Regimen for Previously Untreated CLL - Vimarsana News

Ibrutinib Plus Venetoclax With MRD-Directed Duration of Treatment Is a New Standard of Care Regimen for Previously Untreated CLL

This is the first trial to show that a MRD-guided approach with treatment beyond MRD negativity has a significant advantage over chemotherapy, both in terms of PFS and OS.