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Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells Researchers have designed a new class of TMPRSS2 inhibitors that have shown broad antiviral activity against coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although several vaccines have now been approved for combating coronavirus disease 2019 (COVID-19), there are as yet no safe, targeted and effective drugs available for its treatment. Remdesivir and some other broad-spectrum antivirals have been repurposed (with emergency approval) to treat severe COVID-19, though has...

Study reports vitamin C inhibits SARS-CoV-2 virus main protease Based on structural analysis, researchers found that vitamin C binds to 3CLpro, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease essential in viral replication. In vitro cell inhibition studies also showed vitamin C could inhibit 3CLpro, indicating a possible new antiviral treatment method. Despite the approval of several vaccines to combat the COVID-19 pandemic, the disease continues unabated in many parts of the globe. New viral strains have evolved that may not be neutralized by the antibodies ...

Pfizer-BioNTech mRNA vaccine reduces both symptomatic and asymptomatic COVID-19 infection in case study Follow-up of vaccinated and unvaccinated individuals at St. Jude Children’s Research Hospital, USA, revealed asymptomatic infection reduced by 90% and symptomatic infections reduced by up to 96% in vaccinated people compared to those not vaccinated. The Pfizer/BioNTech mRNA was approved for use in the USA in December 2020. Clinical trials reported an efficacy of 94.8%, and it has been shown to reduce symptomatic infection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

Researchers at the University at Buffalo (UB) have developed a novel 3D-printed scalable water-purifying graphene aerogel with the potential to be used in large industrial wastewater treatment plants.

Study reveals no negative effect of SARS-CoV-2 BNT162b2 vaccination on male fertility Researchers analyzed the sperm parameters of males undergoing fertility treatment and found no effect from the BNT162b2 mRNA severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine.   To combat the COVID-19 pandemic, many countries have started mass vaccination programs. These vaccines have been approved after several safety trials. However, their effect on fertility is still unknown. However, vaccination is still recommended for people who are planning to conceive. Several studies have found a...