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Noxopharm Ltd delivers "promising" results from novel pancreatic cancer study

Noxopharm Ltd delivers "promising" results from novel pancreatic cancer study
proactiveinvestors.com.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from proactiveinvestors.com.au Daily Mail and Mail on Sunday newspapers.

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Noxopharm Ltd and UNSW to present pancreatic cancer research at leading US oncology conference

Noxopharm Ltd and UNSW to present pancreatic cancer research at leading US oncology conference
proactiveinvestors.com.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from proactiveinvestors.com.au Daily Mail and Mail on Sunday newspapers.

Boston , Massachusetts , United-states , American , Phoebe-phillips , Gisela-mautner , Noxopharm-ltd , University-of-new-south-wales , American-association-of-cancer-research , New-south-wales , American-association , Cancer-research

University Of New South Wales: UNSW community recognised in 2022 Queen's Birthday Honours – India Education | Latest Education News | Global Educational News

UNSW academics, alumni and former colleagues have been recognised in this year’s Queen’s Birthday Honours. UNSW warmly congratulates everyone who has been honoured.Professor Mary-Louise McLaws and Dr Kerry Chant, who provided expert advice on COVID-1

Australia , Australians , Australian , Attila-brungs , Vlado-perkovic , Mary-louise-mclaws , Phoebe-phillips , Basil-donovan , Ann-jardine , Deborah-brennan , Peter-saunders , Faculty-of-medicine-health

UNSW researchers find novel way to attack the 'fortress' surrounding pancreatic tumors

UNSW researchers find novel way to attack the 'fortress' surrounding pancreatic tumors
May 17 2021
Tackling the scar tissue that shields pancreatic tumors from effective drug access is a promising advance in a notoriously hard-to-treat cancer.
Dr George Sharbeen and Associate Professor Phoebe Phillips in their lab. Photo: Richard Freeman / UNSW
UNSW medical researchers have found a way to starve pancreatic cancer cells and ‘disable’ the cells that block treatment from working effectively. Their findings in mice and human lab models – which have been 10 years in the making and are about to be put to the test in a human clinical trial – are published today in

United-states , American , Phoebe-phillips , Joshua-mccarroll , Cyrille-boyer , Richard-freeman , George-sharbeen , Cancer-research , American-association-for-cancer-research , University-of-queensland-professor-thomas-davis , Children-cancer-institute , Medicine-health

Pancreatic Cancer May Succumb to "Dual Cell" Approach

Pancreatic Cancer May Succumb to âDual Cellâ Approach
Photo of a human pancreatic tumor section showing SLC7A11 in helper cells (yellow). [UNSW Sydney]
May 13, 2021
To fight pancreatic cancer more effectively, we should do more than attack cancer cells. We should also attack their collaborators, cancer-associated fibroblasts (CAFs). By widening the fight to encompass CAFsâcells that create fibrotic fortresses around pancreatic tumorsâwe may finally overcome a disease that has been known to withstand the most determined sieges.
The castle keep and outer walls of a pancreatic tumor were fired upon simultaneously in research conducted by scientists at the University of New South Wales (UNSW). The scientistsâ weapon of choice? A drug that inhibits SLC7A11, a cystine transporter.

Phoebe-phillips , David-goldstein , Joshua-mccarroll , Cyrille-boyer , Thomas-davis , Cancer-research , University-of-new-south-wales , University-of-queensland , Children-cancer-institute , Medicine-health , New-south-wales , ஃபோப்-பிலிப்ஸ்

Scientists show how to attack 'fortress' surrounding pancreatic cancer tumours

Tackling the scar tissue that shields pancreatic tumours from effective drug access is a promising advance in a notoriously hard-to-treat cancer. ...

United-states , Australia , Australians , Australian , American , Phoebe-phillips , David-goldstein , Joshua-mccarroll , Cyrille-boyer , Richard-freeman , George-sharbeen , Australian-pancreatic-cancer-foundation

Scientists show how to attack the 'fortress' surrounding pancreatic cancer tumours – India Education | Latest Education News India | Global Educational News

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UNSW medical researchers have found a way to starve pancreatic cancer cells and ‘disable’ the cells that block treatment from working effectively. Their findings in mice and human lab models – which have been 10 years in the making and are about to be put to the test in a human clinical trial – are published today in
Cancer Research, a journal of the American Association for Cancer Research.
“Pancreatic cancer has seen minimal improvement in survival for the last four decades – and without immediate action, it is predicted to be the world’s second biggest cancer killer by 2025,” says senior author Associate Professor Phoebe Phillips from UNSW Medicine & Health.

Sydney , New-south-wales , Australia , United-states , Australians , Australian , American , Phoebe-phillips , David-goldstein , Joshua-mccarroll , Cyrille-boyer , George-sharbeen

Scientists show how to attack the 'fortress' surrounding pancreatic cancer tumors

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Credit: UNSW Sydney
UNSW medical researchers have found a way to starve pancreatic cancer cells and 'disable' the cells that block treatment from working effectively. Their findings in mice and human lab models - which have been 10 years in the making and are about to be put to the test in a human clinical trial - are published today in
Cancer Research, a journal of the American Association for Cancer Research.
"Pancreatic cancer has seen minimal improvement in survival for the last four decades - and without immediate action, it is predicted to be the world's second biggest cancer killer by 2025," says senior author Associate Professor Phoebe Phillips from UNSW Medicine & Health.

United-states , Australia , Australians , Australian , American , Phoebe-phillips , David-goldstein , Joshua-mccarroll , Cyrille-boyer , George-sharbeen , Australian-pancreatic-cancer-foundation , University-of-queensland-professor-thomas-davis

New hope for Aussies living with pancreatic cancer

The team found a way to metabolically rewire tumours by targeting a protein called SLC7A11.
"We found that switching off SLC7A11 in mice with pancreatic tumours directly killed pancreatic cancer cells, reduced the spread of tumour cells throughout their body and decreased the scar tissue fortress," said Dr George Sharbeen, a postdoc researcher who led the experimental work.
The promising results were mirrored in experiments using patient tumour samples.
"Our latest advance means today I am the most optimistic and hopeful I have been in my career," said Associate Professor Phillips.
The anti-arthritis drug called sulfasalazine also blocks this protein and will now be repurposed for the Phase II clinical trial.

Australia , Melbourne , Victoria , Australians , Aussies , Phoebe-phillips , George-sharbeen , Associate-professor-phoebe-phillips , Associate-professor , ஆஸ்திரேலியா , மெல்போர்ன்

One to watch: Wasuremono

‘Heart-tugging, oddball pop’: Wasuremono. Photograph: William Southward
‘Heart-tugging, oddball pop’: Wasuremono. Photograph: William Southward
Sat 24 Apr 2021 09.00 EDT
In Japanese, the word “wasuremono” describes something forgotten or left behind – you’ll hear it to describe luggage left on railway platforms. But there’s a hint of longing and nostalgia there too, which chimes perfectly with the technicolour chamber pop of Wasuremono, the band whose members hail not from Tokyo but from Bradford on Avon.
The four met at school, with keyboardist Madelaine Ryan, drummer Isaac Philips and bassist Phoebe Phillips coalescing in 2013 around singer and songwriter Will Southward. By 2016 they’d won praise from Steve Lamacq and Lauren Laverne thanks to their single Cuddling – a song that conjures the spirits of Can, Clinic and 80s children’s TV. Today, Wasuremono’s sound has evolved in synchrony with what sensorially deprived music lovers need: heart-tugging, joyous, oddball pop.

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