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More Than 100 Patients Enrolled in Ongoing SHIELD II Phase 3 Trial of D-PLEX100 for the Prevention of Abdominal Colorectal Surgical Site Infections Unblinded Interim Analysis to be Conducted Once Approximately 400 Patients Complete Their 30-Day Follow-up; Top-line Results Expected in Second Half of 2024 New Preclinical Data Showed OncoPLEX Injected Intratumorally Reduced Tumor Volume and Improved Survival in New Animal Models Recent Successful $16 Million Financing Extends Company’s Cash Runway

PURCHASE AGREEMENT March 29, 2023 GUGGENHEIM SECURITIES, LLC 330 Madison Avenue New York, New... | March 30, 2023

Operação Urbana Água Branca define estímulos como venda de autorização para construção na área; previsão é arrecadar R$ 5 bilhões com certificados e 30% desses recursos serão destinados para moradias de população de baixa renda na Zona Oeste.