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Scientists develop preclinical model of scrub typhus disease

Scientists have developed an animal model of scrub typhus using outbred CD-1 mice. Using the model, they have characterized host susceptibility to the causative pathogen, disease pathogenesis, and immune responses. The study has been published in the journal PLOS Neglected Tropical Diseases. ....

United States , Asia Tsutsugamushi , Image Credit , Southeast Asia , South America , Middle East , Genomics Industry Focus , Animal Model , Immune Response , Ouse Model ,

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a new manuscript, Exosome mediated genetic reprogramming of tumor associated macrophages by exoASO-STAT6 leads to potent monotherapy anti-tumor efficacy, in the American Association for the Advancement of Science's journal, Science Advances. ....

United States , Sriram Sathyanarayanan , Emily Henderson , American Association For The Advancement Of Science , Codiak Biosciences Inc , American Association , Chief Scientific Officer , Precision Medicine , Transcription Factors ,