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Mental illness leading to suicide attempts is prevalent in a large portion of the population especially in low and middle-income nations. There remains a significant social stigma associated with mental illness that can lead to stigmatization of patients. Hence, patients are reluctant to communicate their problems to health care providers. Physicians have difficulty in timely identification of patients at risk for suicide. Novel and rigorously designed strategies are needed to determine the population at risk for suicide. This would be the first step in overcoming the multitude of barriers in ...

Indoor residual spraying (IRS) is one of the key interventions recommended by World Health Organization in preventing malaria infection. We aimed to conduct a systematic review and meta-analysis of global studies about the impact of IRS on malaria control. We searched PubMed, Web of Science, Embase, and Scopus for relevant studies published from database establishment to 31 December 2021. Random-effects models were used to perform meta-analysis and subgroup analysis to pool the odds ratio (OR) and 95% confidence interval (CI). Meta-regression was used to investigate potential factors of hetero...

Strongyloides stercoralis and Trichuris trichiura parasitic infections are two of the many neglected tropical diseases. These parasitic infections are of considerable public health relevance, particularly in resource-limited countries. Moxidectin, a well-established drug in veterinary medicine, is now a Food and Drug Administration (FDA) approved medication for human onchocerciasis. For the past five years, this medication has been under clinical trials to evaluate its efficacy and safetiness in other helminthic infections. Moxidectin might complement the already existing treatment and control...

Delphine Douillet and colleagues investigate the benefit/risk ratio of thromboprophylaxis for patients with leg immobilization after trauma.

Circulating microRNAs demonstrated their potential use as novel noninvasive biomarkers for the diagnosis of Parkinson disease.