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Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis - Vimarsana News

Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis

Benjamin Speich and colleagues investigate whether rates of trial completion and publication have increased over the past decade, the extent to which non-published trials can be identified in registries, and the association between reporting quality of protocols and premature discontinuation or non-publication of trials.

Source: plos.org
Cureus | Outcomes With Left Ventricular Assist Device in End-Stage Renal Disease: A Systematic Review - Vimarsana News

Cureus | Outcomes With Left Ventricular Assist Device in End-Stage Renal Disease: A Systematic Review

Renal dysfunction is a common comorbidity in patients with advanced heart failure who may benefit from mechanical circulatory support (MCS). Unfortunately, renal function may result after left ventricular assist device (LVAD) implantation. The purpose of this study is to examine the outcomes of advanced heart failure patients with end-stage renal disease (ESRD) requiring mechanical circulatory support as a bridge to transplant (BTT) or destination therapy (DT). We searched Medline, Embase, and Cochrane in September 2021. The following keywords were used: left ventricular assist device or LVAD ...

Source: cureus.com
Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis - Vimarsana News

Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis

Amanda Lambert and co-workers study associations between severe mental illness and cardiovascular disease outcomes over time.

Source: plos.org
Cureus | Are We Nuts Over Coconuts? Studying the Effects of Coconut Oil on Low-Density Lipoprotein and Cardiovascular Diseases: A Systematic Review - Vimarsana News

Cureus | Are We Nuts Over Coconuts? Studying the Effects of Coconut Oil on Low-Density Lipoprotein and Cardiovascular Diseases: A Systematic Review

Coconut oil has been gaining popularity recently, especially with health enthusiasts claiming it to be the best fat for consumption. What is the ideal cooking fat? The answer that we are all looking for is just not solely based on one health consequence but several. Our study focuses on the cardiovascular aspects of using coconut oil by its influence on low-density lipoprotein (LDL). Cardiovascular diseases (CVDs) are the major cause of death and mortality worldwide. Hence, they are the focus of this study. For centuries, coconut oil has been used by several populations worldwide who consume ...

Source: cureus.com
Patient-level interventions to reduce alcohol-related harms in low- and middle-income countries: A systematic review and meta-summary - Vimarsana News

Patient-level interventions to reduce alcohol-related harms in low- and middle-income countries: A systematic review and meta-summary

Catherine Staton and co-workers report on evidence about interventions against harmful alcohol use in low- and middle-income countries.

Source: plos.org