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Frontiers | A Prospective Stroke Register in Sierra Leone: Demographics, Stroke Type, Stroke Care and Hospital Outcomes

Introduction Stroke is the second most common cause of adult death in Africa. We report the characteristics of stroke in Freetown, Sierra Leone. Methods A prospective observational register recorded all patients 18 years and over with stroke between May 2019 and April 2020. Stroke was defined according to the WHO criteria. Pearson’s chi squared test was used to examine associations between categorical variables and unpaired t-tests for continuous variables. Multivariable logistic regression was performed to explain in-hospital death, we report odds ratios (OR) and 95% confidence intervals. Results 385 strokes were registered, 315 (81.8%) were first in a lifetime events. Mean age was 59.2 (SD 13.8) and 187 (48.6%) were male. 327 (84.9%) of strokes were confirmed by CT scan. 231 (60.0%) were ischaemic, 85 (22.1%) intracerebral haemorrhage, 11 (2.9%) subarachnoid haemorrhage and 58 (15.1%) undetermined stroke type. The median Barthel Index before stroke was 100 (IQR 100-100) and median ....

Sierra Leone , Capitaled Etat Zone Speciale De Conakry , United Kingdom , City Of , Western Area , Sierra Leoneans , Hulter Asberg , Clin Hypertens , Gordon David Lee , Bendixen Birgitte , Fotso Mefo , Adams Jr , A World Health Organisation , Biomedical Research Centre , World Health Organization , United Kingdom Department Of Health , King College London , Oxford Community Stroke Project , Scientific Review Committee , National Institutes Of Health Stroke Scale , Community Control Of Stroke , Scientific Review Committee On , Monitoring Acute Stroke Care Services , Stata Statistical Software , National Institute For Health Research , Africa World Stroke Congress ,

Inter- and intra-observer agreement in the assessment of the cervical transformation zone (TZ) by visual inspection with acetic acid (VIA) and its implications for a screen and treat approach: a reliability study | BMC Women's Health

In low-resource countries, interpretation of the transformation zone (TZ) using the classification of the International Federation for Cervical Pathology and Colposcopy (IFCPC), adopted by the World Health Organization, is critical for determining if visual inspection with acetic acid (VIA) screening and thermal ablation treatment are possible. We aim to assess inter- and intra-observer agreement in TZ interpretation. We performed a prospective multi-observer reliability study. One hundred cervical digital images of Human papillomavirus positive women (30–49 years) were consecutively selected from a Cameroonian cervical cancer screening trial. Images of the native cervix and after VIA were obtained. The images were evaluated for the TZ type at two time points (rounds one and two) by five VIA experts from four countries (Côte d’Ivoire, Cameroon, Peru, and Zambia) according to the IFCPC classification (TZ1 = ectocervical fully visible; TZ2 = ....

United States , Stata Statistical Software , West Region , Dschang District Hospital , Cancer Prevention , Statistical Software ,