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Maintaining hypercapnia for the first 24 hours in comatose patients resuscitated after out-of-hospital cardiac arrest did not improve outcomes in a large, randomized trial.

High-dose hemodiafiltration led to substantially better survival of patients with end-stage kidney disease compared with conventional hemodialysis after a median 30 months in a large, prospective study.

In the ongoing absence of a reliable biomarker for multiple sclerosis, misdiagnosis is a common, and persistent, problem that potentially puts patients at prolonged and unnecessary risk.

Less aggressive therapy may be appropriate for older adults with early breast cancer. Decisions should be made considering patient preferences and with the help of clinicians skilled at communicating.

Like a guardrail around a painting, oncologists can protect their well-being by fencing off their personal lives, setting boundaries, and saying no to unwanted tasks, various speakers told ASCO attendees.