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Guselkumab Produces Long-Lasting Pharmacodynamic Effects, Disease Improvement in PsA

Continued reductions in serum acute phase proteins and collagen degradation proteins observed in patients with psoriatic arthritis receiving guselkumab may be linked to sustained symptom improvements. ....

Stefan-siebert , University-of-glasgow , American-college-of-rheumatology , Health-assessment-questionnaire , University-of-glasgow-stefan-siebert , Clinical-rheumatology , Psoriatic-area , Severity-index , Psoriatic-arthritis-disease-activity-score , Disease-activity , Psoriatic-arthritis

BE VITAL: Bimekizumab Helps Control, Attenuate Disease Activity in Psoriatic Arthritis

Data from the BE VITAL OLE study, which included patients from the BE COMPLETE and BE OPTIMAL studies, suggests the benefits of bimekizumab in patients with psoriatic arthritis with inadequate response or intolerance to TNF inhibitors were sustained for up to 52 weeis. ....

United-kingdom , Glasgow , Glasgow-city , Scotland , Iain-mcinnes , Emmanuel-caeymaex , University-of-glasgow , Xus-solutions , Life-sciences , University-of-glasgow-professor-ian-mcinnes , American-college-of-rheumatology , College-of-medicinal-veterinary

Treat-to-Target With Tapering Proves Effective in PsA, AxSpA

A trial showed for the first time that disease activity-guided, treat-to-target tapering strategies in both psoriatic arthritis and axial spondyloarthritis are noninferior to those without tapering. ....

Netherlands , Nijmegen , Gelderland , Celia-michielsens , European-congress , Sint-maartenskliniek , Psoriatic-arthritis-disease-activity-score , Ankylosing-spondylitis-disease-activity-score , Daily-clinical , Psoriatic-arthritis , Biologic-therapy , Nonsteroidal-anti-inflammatory-drugs-nsaids