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A High Efficiency One-For-All Nanodroplet for Ultrasound


Supporting Information) under laser irradiation and resulted in PTT of the cancer cells (Figures 5, 6, and 8E). Secondly, the photothermally generated microbubbles enhanced acoustic cavitation (Figures 4 and 6D), their mechanical effects are able to destroy adjacent cancer cells and cause cell death (Figures 6A and 8E). Thus, the combination of PTT and cavitation-mediated cell destruction significantly improved the therapeutic outcomes as compared to the PTT alone (Figures 5, 6 and 8).
Conclusion
A “one-for-all” theranostic [email protected] nanodroplet with low-boiling PFP as the core and PPy that exhibited broad optical absorption constituting the shell was successfully constructed. The [email protected] nanodroplets represent an efficient PTT agent with outstanding photothermal conversion properties that can efficiently transfer NIR light into local hyperthermia for photothermal ablation of tumors. Meanwhile, the liquid-gas phase transition of the PFP cores was al ....

United States , United Kingdom , Aladdin Industry Corporation Shanghai , Hegel Radium Laser Technology Co Ltd , Hitachi Ltd , Xian Jiao Tong University Laboratory Animal Center , Technology Of Xian Jiaotong University , Nikon Instruments Inc , Aladdin Industry Corporation , Thermo Scientific , Xi An Jiao Tong University Laboratory Animal , Animal Experimentation Ethics Committee , Life Science , Xi An Jiaotong , Malvern Instruments , Purkinje General , Dojindo Laboratories , Molecular Devices , Hyperthermia Induced Phase Transition , Acoustic Cavitation , Viability Assay , Digital Sight , Acoustic Cavitation Activity , Enhanced Cancer Therapy , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் ,