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Print this article The National Institutes of Health defended its decision to delete its record of the genetic sequencing of COVID-19 cases from early in the coronavirus pandemic, apparently done at the request of Chinese researchers. The revelation was revealed by a U.S. virologist who discovered the information was scrubbed from the NIH database. This comes as the United States and its allies seek to determine if the virus sprang from a mysterious lab in Wuhan, China, which stymied an earlier investigation by the World Health Organization dismissing the lab theory. “Here I identify a ...

An American scientist recovered the deleted data from cloud storage and published his analysis Tuesday. The paper, “Recovery of deleted deep sequencing data sheds more light on the early Wuhan SARS-CoV-2 epidemic,” suggests that early virus samples from the Wuhan seafood market that until now have been the focus of most studies on the origins of the pandemic “are not fully representative of the viruses actually present in Wuhan at that time.” The paper is not yet peer-reviewed, and its findings should not yet be considered conclusive. The recovered virus samples do not support eit...

Most analyses of the antibody responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have focused on antibodies cloned from memory B cells. This approach has led researchers to conclude that neutralizing antibodies (nAbs) primarily target the receptor-binding domain (RBD) of the virus's spike protein. Voss et al. took a different approach, using proteomic deconvolution of the serum immunoglobulin G antibody repertoire from four COVID-19 convalescent patients. They found that the nAb response was largely directed against epitopes such as the N-terminal domai...