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Biocon Biologics and Viatris Receive European Commission Approval for Kixelle, Biosimilar Insulin Aspart | Proteins and Peptides


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BENGALURU, India I February 12, 2021 I “This is to inform that Biocon Biologics Ltd., a subsidiary of Biocon Ltd. (BSE code: 532523, NSE: BIOCON), has announced that Kixelle, a biosimilar Insulin Aspart co-developed with Viatris Inc. (NASDAQ: VTRS), has received marketing authorization approval from the European Commission following the positive recommendation by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency.
Kixelle, a fast-acting insulin analog indicated for the treatment of diabetes mellitus in adults, adolescents and children aged 1 year and above, has been approved as a 100 units/ml solution for injection in vial and pre-filled pen presentations. ....

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Innovent Announces First Patient Dosed in Phase III Pivotal Trial of IBI310 (CTLA-4) Combined with TYVYT® (sintilimab injection) for the Treatment of First-line Advanced Hepatocellular Carcinoma | Antibodies


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SAN FRANCISCO, CA, USA and SUZHOU, China I February 08, 2021 I Innovent Biologics, Inc. ( Innovent ) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of oncology, metabolic, autoimmune and other major diseases, announces that the first patient has been successfully enrolled and dosed in the randomized, open-label, phase III, multicenter clinical study (NCT04720716) evaluating its IBI310 (anti CTLA-4 monoclonal antibody) in combination with TYVYT® (sintilimab injection) for the first-line treatment of patient with advanced hepatocellular carcinoma (HCC). 
In recent years, immune checkpoint inhibitors have brought new hope to HCC patient population with acceptable safety and encouraging efficacy. NCT04720716 is a randomized, open-label, controlled, multicenter phase III study evaluating the efficacy and safety of IBI310 in combination with TYVYT® (sintilimab inject ....

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Highly Reactive Rubella Spike Ectodomain (E1-E2) Antigen Launched


Feb 08 2021 Read 513 Times
Aalto Bio Reagents is pleased to announce the availability of the first highly reactive recombinant Rubella Spike Ectodomain (E1-E2) antigen, code BM 6428, which has shown exceptional detection of both IgG and IgM antibodies in ELISA and bead-based immunoassays. Purified from recombinant expression in insect cells, this high-quality antigen has guaranteed lot to lot consistency and considerably shorter lead times for large lots compared to native antigen production. Using the protein sequence from the Rubella vaccine strain HPV-77, Aalto Bio Reagents was able to produce a very reliable product, ready for use in the development of highly specific IgG and IgM assays. ....

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Onco-immunology Company Pan Cancer T Launched as Spin-off from Erasmus Medical Center | Proteins and Peptides


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- Seed investment by Swanbridge Capital and Van Herk Ventures with support from Health~Holland
ROTTERDAM, The Netherlands I February 8, 2021 I Pan Cancer T B.V., a biotech spin-off from the Erasmus Medical Center founded by Prof. Dr. Reno Debets (CSO) and Dr. Dora Hammerl (VP R&D), announces the closing of a seed investment and start of operations. Together with Katrien Reynders-Frederix (CEO), the team is committed to the discovery and development of novel TCR therapies against solid tumors such as triple negative breast cancer, bladder cancer, lung cancer, and glioma. Seed investors are Swanbridge Capital and Van Herk Ventures, and the Company is further awarded a Health~Holland grant for a public-private-partnership with Erasmus Medical Center. ....

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