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ENHERTU® Approved in the U.S. for the Treatment of Patients With Previously Treated HER2 Positive Advanced Gastric Cancer | Antibodies


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First HER2 directed medicine approved for patients with gastric cancer in a decade
TOKYO, Japan & MUNICH, Germany & BASKING RIDGE, NJ USA I January 15, 2021 I Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) and AstraZeneca’s
ENHERTU
® (fam-trastuzumab deruxtecan-nxki) has been approved in the U.S. for the treatment of adult patients with locally advanced or metastatic HER2 positive gastric or gastroesophageal junction (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen.
In the U.S., gastric cancer is more frequently diagnosed in the advanced stage, with only approximately 5% of patients surviving five years.
1,2 Approximately one in five gastric cancers are HER2 positive. ....

Baylor University , United States , South Korea , Dave Fredrickson , Ronan Kelly , Daiichi Sankyo , Ww Caruth Jr , Antoine Yver , National Cancer Institute , American Society Of Clinical Oncology , Drug Administration , I Daiichi Sankyo Company , Clinical Development Program , Charlesa Sammons Cancer Center , Oncology Research , Daiichi Sankyo Group , European Medicines Agency , Daiichi Sankyo Company Ltd , Immunology At Baylor University Medical Center , American Cancer Society , Patients With Previously Treated , Advanced Gastric Cancer , Statesi January , Daiichi Sankyo Company , Cancer Center , Baylor University Medical Center ,

ATP and Biolojic Design Launch Aulos Bioscience to Develop Highly Differentiated IL-2 Antibody Approach to Fighting Cancer | Antibodies


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Aulos Bioscience to Present at the 39th Annual J.P. Morgan Healthcare Conference
BOSTON, MA, USA and TEL AVIV, Israel I January 8, 2021 I ATP, a leading life sciences venture capital firm, and Biolojic Design, a biotechnology company that computationally designs functional antibodies, today unveiled Aulos Bioscience, a new company that is developing highly differentiated interleukin-2 (IL-2)-binding monoclonal antibodies as therapeutics against solid tumors.  ATP has committed $40 million in Series A funding to advance Aulos lead molecule from preclinical stage through clinical proof of concept, with human trials expected to start later this year.
ATP created Aulos with Biolojic to develop antibodies with unique properties that we believe hold best-in-class promise among IL-2 targeted therapies, said Michael Ehlers, M.D., Ph.D., Chief Scientific Officer of and venture partner at ATP.   Biolojic has designed elegant and impressively simple molecules t ....

New York , United States , United Kingdom , City Of , San Francisco , Josepha Yanchik , Michael Ehlers , Yechezkel Barenholz , Yanay Ofran , Raj Chopra , Cancer Research United Kingdom Therapeutics Unit , Institute Of Cancer Research , Tokai Pharmaceuticals , Hebrew University Hadassah Medical School , Biolojic Design Launch Aulos Bioscience , Develop Highly Differentiated , Fighting Cancer , Biolojic Design , Israeli January , Aulos Bioscience , Chief Scientific Officer , Chief Executive Officer , Aileron Therapeutics , Novus Therapeutics , Cancer Research , Healthcare Conference ,