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Offering talimogene laherparepvec before surgery compared with surgery alone could improve event-free as well as overall survival in patients with advanced resectable melanoma, a new analysis suggests.
Neoadjuvant vibostolimab plus pembrolizumab has shown antitumor activity in a phase 1/2 trial of patients with stage IIIB-D melanoma.
Third trial testing the approach shows no significant PFS improvement