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The 'Replication Crisis' Could Be Worse Than We Thought, New Analysis Reveals


The Replication Crisis Could Be Worse Than We Thought, New Analysis Reveals
25 MAY 2021
The science replication crisis might be worse than we thought: new research reveals that studies with replicated results tend to be cited less often than studies which have failed to replicate.
 
That s not to say that these more widely cited studies with unreplicated experiments are necessarily wrong or misleading - but it does mean that, for one reason or another, follow-up research has failed to deliver the same result as the original study, yet it still gets loads of citations.
Thus, based on the new analysis, research that is more interesting and different appears to garner more citations than research with a lot of corroborating evidence. ....

United States , Marta Serra Garcia , Uri Gneezy , University Of California , Mp Quot , ஒன்றுபட்டது மாநிலங்களில் , மார்த்தா செர்ரா கார்சியா , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா ,

Detailed text transcripts for TV channel - CNN - 20210523:06:10:00

Steep slope profile. and more of a conical shape. and i want to show you where goma is located. it s this population density right on the lake shore of lake kuvi. that is, again, an area that is away from the actual volcano. and according to authorities, the lava is flowing, again, away from the populated density areas. but that s good news because this area is a highly populated area. you can see rwanda, burundi, and the eastern sections of congo with that dark shade of red and orange. we re talking about over a half a million people according to the latest estimate in goma. and of course they re fearful because they don t want to see a replication of what happened back in january of 2002. we do have the potential for acid rain with this particular volcanic eruption. you get the mixture of sulfur dioxide with moisture in the atmosphere and that leads to a by-product of acid rain. so that s also something we will monitor closely. michael? yeah. i ve been to goma. ....

Population Density , Lake Shore , Conical Shape , Lake Kuvi , Density Areas , Democratic Republic Of Congo , January Of 2002 , A Million , Michael Holmes , Sulfur Dioxide , Acid Rain ,

"Single-Molecule Fluorescence Methods to Study Protein Exchange Kinetic" by Richard R. Spinks, Lisanne M. Spenkelink et al.


Abstract
Recent single-molecule studies have demonstrated that the composition of multi-protein complexes can strike a balance between stability and dynamics. Proteins can dynamically exchange in and out of the complex depending on their concentration in solution. These exchange dynamics are a key determinant of the molecular pathways available to multi-protein complexes. It is therefore important that we develop robust and reproducible assays to study protein exchange. Using DNA replication as an example, we describe three single-molecule fluorescence assays used to study protein exchange dynamics. In the chase exchange assay, fluorescently labeled proteins are challenged by unlabeled proteins, where exchange results in the disappearance of the fluorescence signal. In the FRAP exchange assay, fluorescently labeled proteins are photobleached before exchange is measured by an increase in fluorescence as non-bleached proteins exchange into the complex. Finally, in the two-color ....

Compositional Dynamics , Single Molecule , Upramolecular Complexes ,

Welcome To IANS Live - SCIENCE - Covid: Hepatitis C drugs combined with Remdesivir more effective


Photo Credit: IANS
IANSLive
New York, April 28 (IANS) US researchers have found that combining Remdesivir a drug currently approved for treating Covid-19 patients with repurposed drugs for hepatitis C virus (HCV) is 10 times more effective at slowing down SARS-CoV-2, the virus that causes coronavirus.
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© 2021 IANS India Private Limited. All Rights Reserved.
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Update: 28-April-2021 ....

New York , United States , News Service , India Private , All Rights , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , செய்தி சேவை , இந்தியா ப்ரைவேட் , அனைத்தும் உரிமைகள் ,

Welcome To IANS Live - INTERNATIONAL - Covid: Hepatitis C drugs combined with Remdesivir more effective


Photo Credit: IANS
IANSLive
New York, April 28 (IANS) US researchers have found that combining Remdesivir a drug currently approved for treating Covid-19 patients with repurposed drugs for hepatitis C virus (HCV) is 10 times more effective at slowing down SARS-CoV-2, the virus that causes coronavirus.
To get full access of the story, click here to subscribe to IANS News Service
© 2021 IANS India Private Limited. All Rights Reserved.
The reproduction of the story/photograph in any form will be liable for legal action.
For news, views and gossips, follow IANS at Twitter.
Update: 28-April-2021 ....

New York , United States , News Service , India Private , All Rights , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , செய்தி சேவை , இந்தியா ப்ரைவேட் , அனைத்தும் உரிமைகள் ,