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Escalating Conflicts On US Campuses: Numerous Arrests Amid Pro-Palestinian Demonstrations

The campuses of many American universities have turned into arenas for escalating protests and demonstrations against the backdrop of Israel's war on the Gaza

Gaza , Israel-general- , Israel , New-york , United-states , California , Colombia , Berkeley , Kerala , India , Tel-aviv , The-west-coast

Effect of combination treatment with glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors on incidence of cardiovascular and serious renal events: population based cohort study

Objective To determine whether the combined use of glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter-2 (SGLT-2) inhibitors is associated with a decreased risk of major adverse cardiovascular events and serious renal events compared with either drug class alone among patients with type 2 diabetes, and to assess the effect of the combination on the individual components of major adverse cardiovascular events, heart failure, and all cause mortality.

Design Population based cohort study using a prevalent new-user design, emulating a trial.

Setting UK Clinical Practice Research Datalink linked to Hospital Episode Statistics Admitted Patient Care and Office for National Statistics databases.

Participants Two prevalent new-user cohorts were assembled between January 2013 and December 2020, with follow-up until the end of March 2021. The first cohort included 6696 patients who started GLP-1 receptor agonists and added on SGLT-2 inhibitors, and the second included 8942 patients who started SGLT-2 inhibitors and added on GLP-1 receptor agonists. Combination users were matched, in a 1:1 ratio, to patients prescribed the same background drug, duration of background drug, and time conditional propensity score.

Main outcome measures Cox proportional hazards models were fitted to estimate the hazard ratios and 95% confidence intervals of major adverse cardiovascular events and serious renal events, separately, comparing the GLP-1 receptor agonist-SGLT-2 inhibitor combination with the background drug, either GLP-1 receptor agonists or SGLT-2 inhibitors, depending on the cohort. Secondary outcomes included associations with the individual components of major adverse cardiovascular events (myocardial infarction, ischaemic stroke, cardiovascular mortality), heart failure, and all cause mortality.

Results Compared with GLP-1 receptor agonists, the SGLT-2 inhibitor-GLP-1 receptor agonist combination was associated with a 30% lower risk of major adverse cardiovascular events (7.0 v 10.3 events per 1000 person years; hazard ratio 0.70, 95% confidence interval 0.49 to 0.99) and a 57% lower risk of serious renal events (2.0 v 4.6 events per 1000 person years; hazard ratio 0.43, 0.23 to 0.80). Compared with SGLT-2 inhibitors, the GLP-1 receptor agonist-SGLT-2 inhibitor combination was associated with a 29% lower risk of major adverse cardiovascular events (7.6 v 10.7 events per 1000 person years; hazard ratio 0.71, 0.52 to 0.98), whereas serious renal events generated a wide confidence interval (1.4 v 2.0 events per 1000 person years; hazard ratio 0.67, 0.32 to 1.41). Secondary outcomes generated similar results but with wider confidence intervals.

Conclusions In this cohort study, the GLP-1 receptor agonist-SGLT-2 inhibitor combination was associated with a lower risk of major adverse cardiovascular events and serious renal events compared with either drug class alone.

This study is based on data from the Clinical Practice Research Datalink obtained under license from the UK Medicines and Healthcare products Regulatory Agency. The data are provided by patients and collected by the UK National Health Service as part of their care and support. The interpretation and conclusions contained in this study are those of the authors alone. Because electronic health records are classified as “sensitive data” by the UK Data Protection Act, information governance restrictions (to protect patient confidentiality) prevent data sharing via public deposition. Data are available with approval, through the individual constituent entities controlling access to the data. Specifically, the primary care data can be requested via application to the Clinical Practice Research Datalink (<https://www.cprd.com>).

United-kingdom , Bristol , City-of , Montreal , Quebec , Canada , Canadian , British , Canadian-institutes-of-health-research , Novartis , Setting-united-kingdom-clinical-practice-research-datalink

City where the promise of good health turns to ash

City where the promise of good health turns to ash
bignewsnetwork.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bignewsnetwork.com Daily Mail and Mail on Sunday newspapers.

India , Delhi , Haryana , Panipat , Khukrana , Yamuna , India-general- , Pinki-chahal , Assan-khurd , School-of-behavioural , World-health-organization , Research-scholar

Newsday

the attack was launched by the shia popular mobilisation militia, which is backed by iran. they are also saying that a us fighterjet targeted a vehicle carrying rockets in zummar. we speak now to a research scholar at the australian national university in canberra, and former australian ambassador to lebanon. i want to get your take on these latest strikes coming from within iraq and aimed at us military assets in syria. well, at this stage, _ military assets in syria. well, at this stage, it _ military assets in syria. well, at this stage, it does - military assets in syria. well, at this stage, it does seem i military assets in syria. well, i at this stage, it does seem to be the popular mobilisation forces, the iranian—backed group in iraq. there was that explosion that you mentioned on saturday which did some damage to one of their bases, and this may be the retaliation that the popular mobilisation forces have launched. but they haven't claimed it as yet, as far as

Us , Attack , Militia , Iran , Vehicle-carrying-rockets , Zummar , Popular-mobilisation , Shia , Fighterjet , Ambassador , Lebanon , Strikes

Research: Repeat Blast-Related Brain Injury in US Special Forces

Research: Repeat Blast-Related Brain Injury in US Special Forces
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Massachusetts , United-states , University-of-south-florida , Florida , American , Natalie-gilmore , Brianl-edlow , Yelenag-bodien , Institute-of-applied-engineering , United-states-special-operations , Us-department-of-defense , Research-scholar

Study identifies signs of repeated blast-related brain injury in active-duty United States Special Operations Forces

Study identifies signs of repeated blast-related brain injury in active-duty United States Special Operations Forces
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United-states , Massachusetts , American , Yelenag-bodien , Brianl-edlow , Natalie-gilmore , Institute-of-applied-engineering , Neurology-at-harvard-medical-school , Research-scholar , University-of-south-florida , United-states-special-operations , Proceedings-of-the-national-academy-sciences

sustainability News, Reviews and More - Make: DIY Projects and Ideas for Makers

sustainability News, Reviews and More - Make: DIY Projects and Ideas for Makers
makezine.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from makezine.com Daily Mail and Mail on Sunday newspapers.

California , United-states , Chiara-cecchini , World-economic-forum , Food-innovation-program , Research-affiliate-at-institute , Barilla-center-food-nutrition-foundation , Research-scholar-at-food-science , Food-institute , Future-food , Research-scholar , Food-science

Individual Research Results Should Be Shared With Participants More Often - NAS

Individual Research Results Should Be Shared With Participants More Often - NAS
science20.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from science20.com Daily Mail and Mail on Sunday newspapers.

Salt-lake-city , Utah , United-states , Vermont , Columbia-university , New-york , Rockefeller-university , Washington , Pelham-manor , Burlington , Michigan , Baylor-university

Undergraduate Research Events | Undergraduate Education

Undergraduate Research Events | Undergraduate Education
utdallas.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from utdallas.edu Daily Mail and Mail on Sunday newspapers.

Dallas , Texas , United-states , Research-resume-workshop , Ut-dallas-research-matching-portal , Research-match-day , Office-of-research , Research-resume-workshop-part , Research-scholar-awards-poster-contest-symposium , Research-scholar , Research-scholar-awards-poster-contest-finals

Beat PCOD with Exercise - News Today | First with the news

Beat PCOD with Exercise - News Today | First with the news
newstodaynet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newstodaynet.com Daily Mail and Mail on Sunday newspapers.

Hindustan , India-general- , India , Department-of-physical-education , Research-scholar-at-hindustan-institute-of-science , Research-scholar , Hindustan-institute , Assistant-professors , Polycystic-ovary-disease , Physical-education , Sports-science