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Oral APX3330 Receives FDA Nod for Phase 3 Endpoint in Diabetic Retinopathy

Ocuphire's end-of-phase 2 meeting with the FDA supports APX3330's phase 3 advancement, with 3-step worsening in binocular DRSS score as the primary endpoint. ....

United States , Arshad Khanani , David Brown , George Magrath , Drug Administration , Ocuphire Pharma Inc , American Academy Of Ophthalmology , Sierra Eye Associates , Special Protocol Assessment , Retina Consultants , Annual American Academy ,

Diabetic Retinopathy Usually No Worse With Semaglutide in T2D

Few eyes with no or background DR or mild or moderate nonproliferative diabetic retinopathy have worsening of DR at 3, 6, 12, 24 months. ....

United States , San Francisco , Zeeshan Haq , American Academy Of Ophthalmology , Healthday News , American Academy , Retina Consultants ,

Study Shows Tarcocimab May Improve Diabetic Retinopathy

A phase 3 trial showed that tarcocimab, a biopolymer with a vascular growth factor antibody, improved vision and anatomical markers in patients with early stage diabetic retinopathy. ....

Friuli Venezia Giulia , United States , Paolo Lanzetta , Charles Wykoff , Kodiak Sciences , University Of Udine , American Academy Of Ophthalmology , Blanton Eye Institute Of Houston Methodist Hospital , Retina Consultants , Blanton Eye Institute , Houston Methodist , American Academy , Diabetic Retinopathy Severity Scale , Retinal Disease , Diabetes Mellitus Type 2 , Iabetes Mellitus Type Ii , Type 2 Diabetes , Microvascular Complications Of Diabetes , Diabetic Retinopathy , Monoclonal Antibody , Macular Edema , Diabetic Macular Edema , Clinical Management , Macular Degeneration , Ge Related Macular Degeneration Armd ,

AAO: Diabetic Retinopathy Usually No Worse With Semaglutide in T2D

THURSDAY, Nov. 9, 2023 (HealthDay News) For patients with type 2 diabetes mellitus, most eyes have no worsening of diabetic retinopathy (DR) after initiation of semaglutide, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Nov. 3 to 6 in San Francisco. Zeeshan Haq, M.D., from ....

United States , San Francisco , Zeeshan Haq , American Academy Of Ophthalmology , Healthday News , American Academy , Retina Consultants ,

Ocugen, Inc. Announces First Patient Dosed in Phase 1/2 Clinical Trial Evaluating the Safety and Efficacy of OCU410ST—Modifier Gene Therapy—for Stargardt Disease

MALVERN, Pa., Nov. 10, 2023 Ocugen, Inc. , a biotechnology company focused on discovering, developing, and commercializing novel gene and cell therapies, biologics, and vaccines, today. ....

United States , Charles Wykoff , Shankar Musunuri , Ocugen Inc , Head Of Communications , Exchange Commission , Nuclear Hormone Receptor , Stargardt Disease , Orphan Receptor , Retina Consultants , Private Securities Litigation Reform Act ,