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Oral IL-23 Blocker for Psoriasis Promising: Phase 2b Study - Vimarsana News

Oral IL-23 Blocker for Psoriasis Promising: Phase 2b Study

An investigational IL-23R antagonist demonstrated significantly greater efficacy across all doses in patients with moderate to severe psoriasis compared with placebo at week 16 in the FRONTIER 1 study.

Janssen Announces Positive Topline Results for JNJ-2113--a Novel, First and Only Oral IL-23 Receptor Antagonist Peptide in Development for Moderate-to-Severe Plaque Psoriasis - Vimarsana News

Janssen Announces Positive Topline Results for JNJ-2113--a Novel, First and Only Oral IL-23 Receptor Antagonist Peptide in Development for Moderate-to-Severe Plaque Psoriasis

/PRNewswire/ -- The Janssen Pharmaceutical Companies of Johnson & Johnson today announced positive topline results from its Phase 2b FRONTIER 1 clinical trial...

Ruxolitinib Cream 1.5% Led to Rapid, Significant Reduction in Pruritus for Atopic Dermatitis - Vimarsana News

Ruxolitinib Cream 1.5% Led to Rapid, Significant Reduction in Pruritus for Atopic Dermatitis

New phase 2 data from the SCRATCH-AD trial found that ruxolitinib 1.5% showed strong results for rapidly reducing itch in eczema patients, an improvement that continued over 28 days.

Incyte Announces Results from SCRATCH-AD Trial Demonstrating Substantial and Rapid Itch Reduction in Patients with Mild-Moderate Atopic Dermatitis Treated with Opzelura® (ruxolitinib) Cream - Vimarsana News

Incyte Announces Results from SCRATCH-AD Trial Demonstrating Substantial and Rapid Itch Reduction in Patients with Mild-Moderate Atopic Dermatitis Treated with Opzelura® (ruxolitinib) Cream

– Adult patients with atopic dermatitis treated with Opzelura experienced rapid and substantial improvement in itch, which was sustained through Day 28 ... | May 1, 2023

Topical Delgocitinib Effective for Hand Eczema in Phase 3 Trial - Vimarsana News

Topical Delgocitinib Effective for Hand Eczema in Phase 3 Trial

The phase 3 study evaluated delgocitinib, an investigational topical pan-JAK inhibitor that inhibits activation of the JAK-STAT pathway and targets key mediators of chronic hand eczema.