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Adam Tait III Journal Register News SHAMONG-A Shamong resident since 1975, Bill Lampman has become increasingly upset over what he claims is an over-emphasis on youth athletic programs, combined with what he calls a serious lack of services in other areas. While stressing that he’s not opposed to the youth programs, which he concedes attract […]
The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.
<p>Researchers have developed a human <em>in vitro</em> model that closely mimics the complexities of radiation-induced lung injury (RILI) and radiation dose sensitivity of the human lung. Using a previously developed microfluidic human Lung Alveolus Chip lined by human lung alveolar epithelial cells interfaced with lung capillary cells to recreate the alveolar-capillary interface <em>in vitro</em>, the researchers recapitulated many of the hallmarks of RILI, including radiation-induced DNA damage in lung tissue, cell-specific changes in...