Stay updated with breaking news from Robin choi. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Friends and family of a Fairfax County woman who died a month after a hit-and-run put her in the hospital is pleading for help to bring the driver who killed her to justice.
Corporate Citizenship & Giving Guide 2022 - Addressing Affordable Housing, Homelessness, Small Business and Financial Health sfvbj.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sfvbj.com Daily Mail and Mail on Sunday newspapers.
Credit: The Wistar Institute PHILADELPHIA -- (Jan. 12, 2021) -- Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published today in the journal Nature Communications. Checkpoint inhibitors revolutionized therapeutic options for advanced melanoma. However, only a fraction of patients respond to this treatment and some relapse due to reemergence of therapy-resistant lesions. "To better understand why some cancers do not respond or become resistant to checkpoint therapies, we need more preclinical models that mimic the human tumor immune environment," said Rajasekharan Somasundaram, Ph.D., a member of The Wistar Institute Melanoma Research Center, who is the first and corresponding author of the paper.