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Psychedelics are back in vogue, but some doctors, researchers and indeed patients are more cautious about results
Current evidence leaves more questions than answers Psilocybin and other psychedelics are under investigation for use in several mental health conditions, including depression.1 Psilocybin, a prodrug that naturally occurs in “magic” mushrooms (genus Psilocybe ), has been used for ritualistic purposes by indigenous populations of Central-North America for thousands of years.2 Its active metabolite, psilocin, targets 5-hydroxytryptamine type 2A receptors, whose potent activation of serotonergic pathways is largely responsible for producing psychedelic effects.3 Both rapidly induced changes i...
Meta-analysis raises questions regarding safety, clinical practice use