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Targeted Treatments for GVHD

The GVHD experts discuss recent advancements in chronic GVHD treatment, focusing on agents ruxolitinib, ibrutinib, and belumosudil and their mechanisms of action. The panel emphasizes the need for ongoing research and clinical trials to refine treatment strategies. ....

United States , Dana Farber Cancer Institute , Corey Cutler , Bin Chen , Mitchell Horwitz , Hannah Choe , Ohio State University , Cell Therapy Program At Massachusetts , Professor Of Medicine At Harvard Medical School , Marrow Transplant Program At Duke University , Cell Therapy Program , Massachusetts General Hospital , Harvard Medical School , Stem Cell Transplant Program , Adult Blood , Marrow Transplant Program , Duke University , Assistant Professor , Ohio State , Yi Bin Chen , Chronic Graft Versus Host Disease , Jak Stat Inhibitor , Btk Inhibitor , Rock2 Inhibitor , Fibrotic Pathway , Germinal Center ,

Corticosteroids and Clinical Trial Design in Chronic GVHD

Drs Yi-Bin Chen, Corey Cutler, Hannah Choe, and Mitchell Horwitz discuss the complexities of chronic GVHD management, highlighting recent developments and efforts to reduce reliance on steroids. ....

United States , Dana Farber Cancer Institute , Bin Chen , Mitchell Horwitz , Corey Cutler , Hannah Choe , Marrow Transplant Program At Duke University , Professor Of Medicine At Harvard Medical School , Cell Therapy Program At Massachusetts , Ohio State University , Cell Therapy Program , Massachusetts General Hospital , Harvard Medical School , Stem Cell Transplant Program , Adult Blood , Marrow Transplant Program , Duke University , Assistant Professor , Ohio State , Chronic Graft Versus Host Disease , High Dose Corticosteroid , Clinical Trial Design , Integrate Trial , Early Treatment , Patient Stratification , Steroid Free Approach ,

JAKAFI (Ruxolitinib) Emerging Drug Insights and Market

Dublin, Jan. 24, 2024 (GLOBE NEWSWIRE) The ....

United States , United Kingdom , Incyte Corporation , Clinical Development , Drug Insight , Market Forecast , Topics Covered , Bronchiolitis Obliterans , Late Stage Emerging Therapies , Research And Markets , Clinical Development , Drug Discovery , Emerging Drug , Ematological Drugs ,

Dr Tantravahi on the Efficacy of Selinexor Plus Ruxolitinib in JAK Inhibitor–Naive Myelofibrosis

Srinivas K. Tantravahi, MBBS, MRCP, discusses the preliminary efficacy of selinexor in combination with ruxolitinib in patients with JAK inhibitor–naive myelofibrosis, as seen in the phase 1 XPORT-MF-034 trial. ....

United States , Srinivask Tantravahi , University Of Utah Huntsman Cancer Institute , Utah Huntsman Cancer Institute , Reviewing Research Efforts Seeking To Raise The Bar In Myelofibrosis , Onclive Tv , Phase 1 3 Xport Mf 034 Trial , Jak Inhibitor Naive ,

Dr Kuykendall on the Efficacy of Pelabresib Plus Ruxolitinib in JAK Inhibitor–Naive Myelofibrosis

Andrew Kuykendall, MD, discusses the efficacy of the combination of pelabresib and ruxolitinib in patients with JAK inhibitor–naive myelofibrosis based on data from the phase 3 MANIFEST-2 trial. ....

Andrew Kuykendall , Moffitt Cancer Center , Department Of Malignant Hematology , Malignant Hematology , Pelabresib Cpi 0610 , Hase 3 Manifest 2 Trial Nct04603495 ,