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Gene Therapy Shows Promise in Congential Blindness Patients


Gene Therapy Shows Promise in Congential Blindness Patients
by Angela Mohan on 
April 20, 2021 at 11:14 AM
New gene therapy for a congenital blindness was found to be safe and improved patients vision, according to a clinical trial led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.
This gene therapy delivers copies of GUCY2D gene to the eyes of patients who have severe vision impairments caused by mutations in the gene, according to the study, published in the journal
iScience.
We found sustained improvements in both day and night vision, even with a relatively low dose of the gene therapy, said study lead author Samuel G. Jacobson, MD, PhD, a professor of Ophthalmology in the Perelman School of Medicine. ....

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Gene therapy shows promise in initial trial for patients with childhood blindness: Study


Gene therapy shows promise in initial trial for patients with childhood blindness: Study
ANI |
Updated: Apr 20, 2021 17:11 IST
Philadelphia (Pennsylvania) [US], April 20 (ANI): A new gene therapy for one of the most common forms of congenital blindness was safe and improved patients vision, according to initial data from a clinical trial led by researchers.
The novel study was led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.
The therapy delivers working copies of GUCY2D to the eyes of patients who have severe vision impairments caused by mutations in the gene. Each of the first three treated patients experienced an improvement in some aspects of vision, without serious side effects, as per the new study published in the journal iScience. ....

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Gene therapy for common forms of congenital blindness shows promise to improve vision


Gene therapy for common forms of congenital blindness shows promise to improve vision
A new gene therapy for one of the most common forms of congenital blindness was safe and improved patients vision, according to initial data from a clinical trial led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.
The therapy delivers working copies of GUCY2D to the eyes of patients who have severe vision impairments caused by mutations in the gene. Each of the first three treated patients experienced improvement in some aspects of vision, without serious side effects, according to the new study, published in the journal ....

Samuelg Jacobson , Arturv Cideciyan , Emily Henderson , University Of Pennsylvania , Perelman School Of Medicine , Scheie Eye Institute , Perelman School , Study Lead Author , Gene Therapy , Clinical Trial , Leber Congenital Amaurosis , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா , பெரல்மேன் பள்ளி ஆஃப் மருந்து , ஸ்ச்சேஎ கண் நிறுவனம் , பெரல்மேன் பள்ளி , படிப்பு வழி நடத்து நூலாசிரியர் ,