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Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

Hawaii , United-states , Lopa-mishra , Sanjayak-satapathy , Herbert-yu , Fellanza-cacaj , Sahara-john , Gulru-sharifova , Xiaochun-yang , Patricias-latham , Xiyan-xiang , Nyasha-chambwe

Blood Proteomic Markers Stratify HCC Risk in Cirrhosis Patients

Blood Proteomic Markers Stratify HCC Risk in Cirrhosis Patients
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Hawaii , United-states , Patricias-latham , Christina-brennan , Hai-huang-srinivasan-dasarathy , Herbert-yu , Nyasha-chambwe , Xiyan-xiang , Richardj-dima , Sanjayak-satapathy , Kirti-shetty , Jamesm-crawford

Genes Linked to Hepatocellular Carcinoma Treatment & Prevention

Genes Linked to Hepatocellular Carcinoma Treatment & Prevention
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United-states , Georgetown-university , District-of-columbia , Washington , Hawaii , David-bernstein , Atoosa-rabiee , Gregorym-grimaldi , Xiyan-xiang , Jonathan-weinstein , Kirti-shetty , Lopa-mishra

One-year kidney allograft outcomes do not differ by hepatitis C status of donor


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IMAGE: Recipients of kidneys from donors infected with HCV have similar kidney allograft function and probability of rejection in the first year after transplantation compared to those who received kidneys from...
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Credit: AJKD, 2020
Study published in the
American Journal of Kidney Diseases (AJKD) shows that kidney allograft outcomes one year post-transplantation in hepatitis C virus (HCV)-negative recipients do not differ by the HCV status of the donor.
Transplant centers are increasingly willing to transplant kidneys from hepatitis C (HCV)-infected donors to HCV-negative recipients. Data on the long-term outcomes following these recipients are sparse. The aim of this single-center, retrospective study was to compare 1-year kidney outcomes in HCV-negative transplant recipients who received an organ either from a donor with or without HCV infection. The 1-year post-transplant kidney outcomes (including allograft function, development of de novo donor specific antibodies, findings on for-cause and surveillance protocol graft biopsies) were similar in these two groups of recipients.

United-states , American , Makoto-tsujita , Csabap-kovesdy , Jiten-kothadia , Satheesh-nair , Vasanthi-balaraman , Jamesd-eason , Pradeep-sb-podila , Uchennaa-agbim , Benedict-maliakkal , Anshul-bhalla