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Transcripts For BBCNEWS BBC News At Five 20171211

Our main story is that snow and freezing temperatures are causing widespread disruption in many parts of the uk. Heathrow airport is trying to clear a backlog of hundreds of flights, the port of calais is closed, while roads and rail have been badly affected. Its all making travel difficult and even hazardous. More than a thousand schools failed to open this morning because of the snow. Hundreds of homes, mainly in wales, and a belt across the centre of england, are without power. The forecasters say temperatures could fall in places tonight to as low as 12 celsius. Our correspondent phil mackie reports. A large swathe of Central England and most of wales woke up to a winter wonderland, but the morning commute was tricky, many areas saw their heaviest snowfall for seven years. Some areas saw 20 centimetres, which froze when temperatures plummeted. Driving conditions were extremely dangerous, and the
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SfN 2023: Lessons from Huntington's successes, and failures

The gene for Huntington’s disease (HD) “was cloned in 1993, and everyone thought there was going to be a treatment right around the corner,” Sarah Tabrizi told the audience at the 2023 Annual Meeting of the Society for Neuroscience. Then, “it took 25 years for the first trial targeting the Huntington gene.” ....

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