Frontiers | Phenotypic and Genotypic Co-receptor Tropism Testing in HIV-1 Epidemic Region of Tanzania Where Multiple Non-B Subtypes Co-circulate
2Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania 3Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan 4Muhimbili National Hospital, Dar es Salaam, Tanzania HIV human immunodeficiency virus type I (HIV-1) entry inhibitor potency is dependent on viral co-receptor tropisms and thereby tropism determination is clinically important. However, phenotypic tropisms of HIV-1 non-B subtypes have been poorly investigated and the genotypic prediction algorithms remain insufficiently validated. To clarify this issue, we recruited 52 treatment-naïve,...
Source: frontiersin.org