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Scientists are using MRI scans to understand how mental illness shows up in the bran. But new research raises concerns that existing studies are not reliable because the sample sizes are too small.
Small MRI studies inflate effect sizes, leaving the brain imaging research literature cluttered with false positives.
Low participant numbers render the results of many studies based on brain scans unreliable, an analysis finds.
Researchers have long used imaging technology to try to understand mental-health ailments. But with relatively few participants, such studies may not be producing valid findings.
The ability to image our brains has advanced neuroscience research hugely. But new research casts significant doubt on the statistical validity of a swathe of neuroimaging experiments.