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People with delirium episodes are at higher risk of developing dementia, reveals study

People with delirium episodes are at higher risk of developing dementia, reveals study
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United-kingdom , Australia , Australian , British , Emily-gordon , Shlomo-berkovsky , Jeffrey-braithwaite , Partnership-centre-for-health-system-sustainability , Macquarie-university , Uq-centre-for-health-systems-research , Australian-institute-of-health-innovation , University-of-queensland

Delirium and incident dementia in hospital patients in New South Wales, Australia: retrospective cohort study

Objectives To determine the strength and nature of the association between delirium and incident dementia in a population of older adult patients without dementia at baseline.

Design Retrospective cohort study using large scale hospital administrative data.

Setting Public and private hospitals in New South Wales, Australia between July 2001 and March 2020.

Participants Data were extracted for 650 590 hospital patients aged ≥65 years. Diagnoses of dementia and delirium were identified from ICD-10 (international classification of diseases, 10th revision) codes. Patients with dementia at baseline were excluded. Delirium-no delirium pairs were identified by matching personal and clinical characteristics, and were followed for more than five years.

Main outcome measures Cox proportional hazards models and Fine-Gray hazard models were used to estimate the associations of delirium with death and incident dementia, respectively. Delirium-outcome dose-response associations were quantified, all analyses were performed in men and women separately, and sensitivity analyses were conducted.

Results The study included 55 211 matched pairs (48% men, mean age 83.4 years, standard deviation 6.5 years). Collectively, 58% (n=63 929) of patients died and 17% (n=19 117) had a newly reported dementia diagnosis during 5.25 years of follow-up. Patients with delirium had 39% higher risk of death (hazard ratio 1.39, 95% confidence interval 1.37 to 1.41) and three times higher risk of incident dementia (subdistribution hazard ratio 3.00, 95% confidence interval 2.91 to 3.10) than patients without delirium. The association with dementia was stronger in men (P=0.004). Each additional episode of delirium was associated with a 20% increased risk of dementia (subdistribution hazard ratio 1.20, 95% confidence interval 1.18 to 1.23).

Conclusions The study findings suggest delirium was a strong risk factor for death and incident dementia among older adult patients. The data support a causal interpretation of the association between delirium and dementia. The clinical implications of delirium as a potentially modifiable risk factor for dementia are substantial.

The data used in this study are available to the public through application to the Centre for Health Record Linkage (see [www.cherel.org.au][1] for more information). The analysis script (R markdown file) is available for download from <https://espace.library.uq.edu.au/view/UQ:dfc4e74>

[1]: http://www.cherel.org.au

Australia , Australian , Shlomo-berkovsky , Ruthe-hubbard , Hao-xiong , Emilyh-gordon , Australian-frailty-network , Partnership-centre-for-health-systems-sustainability , Partnership-centre-for-health-system-sustainability , Centre-for-health-record-linkage , Health-records , Hospital-elder-life-program

Business.Scoop » Fujitsu & Macquarie University Establish New Research Lab To Accelerate Development Of Human Sensing & Generative AI

Business Scoop provides news and views on Business and Markets from New Zealand

Tokyo , Japan , Australia , S-bruce-dowton , Genta-suzuki , Enrico-coiera , Shlomo-berkovsky , Amin-beheshti , Sohan-domingo , Toshihiro-sonoda , Alfee-lee , Research-project-overview

Fujitsu & Macquarie University Establish New Research Lab To Accelerate Development Of Human Sensing & Generative AI

TOKYO, Nov 30, 2023 - (JCN Newswire) - Fujitsu Limited and Macquarie University today announced the establishment of the Fujitsu Macquarie AI Research Lab at Macquarie University, as part of the Fujitsu Small Research Lab ( 1 ) program. It aims to strengthen ...

Japan , Tokyo , Australia , Alfee-lee , Genta-suzuki , Enrico-coiera , Shlomo-berkovsky , Toshihiro-sonoda , Sohan-domingo , Amin-beheshti , S-bruce-dowton , Macquarie-university-sydney

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Japan , Australia , Tokyo , Alfee-lee , Toshihiro-sonoda , Sohan-domingo , S-bruce-dowton , Shlomo-berkovsky , Enrico-coiera , Amin-beheshti , Genta-suzuki , Fujitsu-limited

Fujitsu Ltd: Fujitsu and Macquarie University establish new research lab to accelerate development of human sensing and generative AI technologies

Fujitsu Ltd: Fujitsu and Macquarie University establish new research lab to accelerate development of human sensing and generative AI technologies
finanznachrichten.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from finanznachrichten.de Daily Mail and Mail on Sunday newspapers.

Japan , Australia , Tokyo , Sohan-domingo , Alfee-lee , Genta-suzuki , Toshihiro-sonoda , Enrico-coiera , Amin-beheshti , S-bruce-dowton , Shlomo-berkovsky , Stefan-klotter

Fujitsu and Macquarie University establish new research lab to accelerate development of human sensing and generative AI technologies

Fujitsu and Macquarie University establish new research lab to accelerate development of human sensing and generative AI technologies
jcnnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from jcnnewswire.com Daily Mail and Mail on Sunday newspapers.

Japan , Australia , Tokyo , Genta-suzuki , Alfee-lee , Toshihiro-sonoda , S-bruce-dowton , Amin-beheshti , Enrico-coiera , Shlomo-berkovsky , Sohan-domingo , Macquarie-university-hospital

Fujitsu And Macquarie University Establish New Research Lab To Accelerate Development Of Human Sensing And Generative AI Technologies

Fujitsu And Macquarie University Establish New Research Lab To Accelerate Development Of Human Sensing And Generative AI Technologies
menafn.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from menafn.com Daily Mail and Mail on Sunday newspapers.

Tokyo , Japan , Australia , Amin-beheshti , S-bruce-dowton , Toshihiro-sonoda , Genta-suzuki , Alfee-lee , Enrico-coiera , Shlomo-berkovsky , Sohan-domingo , Fujitsu-limited