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In a real-world setting, less than a quarter of patients diagnosed with depression improved with medication, hospitalization, and therapy.

Adjunctive psychotherapy confers no additional benefit over antidepressant therapy for major depression. Researchers question whether that's because of limited access to psychotherapeutic treatment.

Antidepressants are the first-choice treatment for severe depression. Antidepressant use is often supplemented by psychotherapy.

For severe depression, antidepressants are the first line of treatment. Psychotherapy is often used along with antidepressants. Now, findings from a large

For more than twenty years now, international research into the endocannabinoid system in the human body has been seeking to understand the mode of action of cannabis and its constituents.