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H) CCND1 expression in BC patients revealed by GEPIA website (
I) the β-catenin and GSK3β expression as well as the extent of GSK3β phosphorylation in MCF-7 and T47D parents and resistant cells. Data are displayed in the form of mean ± SD. All experiments were repeated at least three times. In panel (
B) two-way ANOVA along with Tukey’s multiple comparison was applied, while in panel (
D, E and
p 0.05,
p 0.01.
Abbreviations: miR, microRNA; FOXO1, forkhead box O1; CCND1, cyclin D1; SD, standard deviation; ANOVA, analysis of variance.
We predicted that FOXO1 could bind to the promoter sequence of CCND1 through the JASPAR website ( ....

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