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'Cutting the cable' between CD8+ T and T regulatory cells enhances checkpoint immunotherapy - Vimarsana News

'Cutting the cable' between CD8+ T and T regulatory cells enhances checkpoint immunotherapy

Checkpoint immunotherapy utilizing PD-1 blockade has become the standard of care for metastatic melanoma. While this treatment is effective in 40% of patients, the other 60% develop resistance, leading to tumor regrowth. A multidisciplinary research team led by the University of California, Irvine has identified a new strategy that could enhance the therapeutic effectiveness of this therapy by targeting the communication between immune cells within the tumor.

Study models how ketamine's molecular action leads to its effects on the brain - Vimarsana News

Study models how ketamine's molecular action leads to its effects on the brain

New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function.

Study offers new insights into how ketamine works - Vimarsana News

Study offers new insights into how ketamine works

A World Health Organization Essential Medicine, ketamine is widely used at varying doses for sedation, pain control, general anesthesia and as a therapy for treatment-resistant depression.

Spoleto changes Charleston venue due to construction | Charleston Scene - Vimarsana News

Spoleto changes Charleston venue due to construction | Charleston Scene

Due to construction delays on the Simons Center for the Arts, the Robinson Theatre will no longer be available for Spoleto, with new venues added to the lineup.

For people who speak many languages, there's - Vimarsana News

For people who speak many languages, there's

<p>An MIT study of polyglots found the brain&rsquo;s language network responds more strongly when hearing languages a speaker is more proficient in &mdash; and much more weakly to the speaker&rsquo;s native language.</p>