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A new method can track changes in live cell gene expression over extended periods of time. Based on Raman spectroscopy, the method doesn’t harm cells and can be performed repeatedly.
Using more than 2 million cells from over 400 postmortem brain samples, MIT researchers performed the largest-scale analysis of the genomic, epigenomic, and transcriptomic changes that occur in every cell type in the brains of Alzheimer’s patients.
The tumor-immune evasion cell networks in clear cell renal cell carcinoma may be captured and classified using imaging mass cytometry, an orthogonal approach with the potential for increased cost-efffectiveness and accuracy compared with single-cell RNA sequencing.
Olfactory tissue biopsies help researchers discover the mechanism responsible for COVID-19-related loss of smell, along with other long COVID symptoms.
MIT and Harvard Medical School researchers mapped out many of the cells, genes, and cellular pathways that are modified by exercise or a high-fat diet. They hope their findings will help guide the design of drugs that might mimic some beneficial effects of exercise.