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Chromatin remodeling tied to altered splicing in autism model | Spectrum

Published: February 7, 2023

Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.

Source: spectrumnews.org

Related Topics:

Rhode IslandUnited StatesBrown UniversityUniversity Of Texas Southwestern Medical CenterUnited KingdomMaria ChahrourGamsiz UzunBrown University In ProvidenceUniversity Of ExeterSofia LizarragaHuman Molecular GeneticsTexas Southwestern Medical CenterJonathan MillEce Gamsiz Uzun

Autism-tied gene ZNF462 keeps developing neurons on track | Spectrum

Published: February 1, 2023

The gene, linked to a little-known condition called Weiss-Kruszka syndrome, prevents embryonic stem cells from deviating from their neuronal destiny.

Source: spectrumnews.org

Related Topics:

Rhode IslandUnited StatesLos AngelesOliver BellPaul KruszkaBrown University In ProvidenceUniversity Of Southern CaliforniaNational Human Genome Research Institute In BethesdaSouthern CaliforniaNational Human Genome Research InstituteNature Cell BiologySofia LizarragaBrown University