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Enhancer-gene mapping with SCENT method offers insights into disease mechanisms

Genetic studies of diseases map segments of the genome driving disease. But to understand how those changes contribute to disease progression, it is important to understand how they may alter gene regulation of disease genes in cell populations assumed to be driving disease.

Soumya-raychaudhuri , Brigham-division-of-rheumatology , Mass-general-brigham ,

Researchers develop statistical method for genetic mapping of autoimmune diseases

Researchers develop statistical method for genetic mapping of autoimmune diseases
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Soumya-raychaudhuri , Saori-sakaue , Brigham-division-of-rheumatology , Nature-genetics , Mass-general-brigham ,

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

Soumya-raychaudhuri , Danielle-ellis , Michael-brenner , Brigham-division-of-rheumatology , Medicines-partnership-rheumatoid-arthritis , Broad-institute , Mass-general-brigham , Systemic-lupus-erythematosus , Arthritis , Edicine , Recision-medicine , Heumatoid-arthritis

Cellular 'atlas' built to guide precision medicine treatment of rheumatoid arthritis

Cellular 'atlas' built to guide precision medicine treatment of rheumatoid arthritis
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Soumya-raychaudhuri , Michael-brenner , Broad-institute , Medicines-partnership-rheumatoid-arthritis , Brigham-division-of-rheumatology , Mass-general-brigham , Systemic-lupus-erythematosus ,

Cellular Atlas Developed for Precision Rheumatoid Arthritis Care

Cellular Atlas Developed for Precision Rheumatoid Arthritis Care
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