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Mixed Results with Refined Treatment Strategies for Rheumatic Diseases


May 5, 2021
Therapeutic drug monitoring, half-dosing may not be ready for prime-time
Therapeutic drug monitoring (TDM) for patients with immune-mediated inflammatory diseases did not lead to better clinical remission rates, while routine dose reduction of anti-rheumatic drugs for patients with rheumatoid arthritis (RA) in remission offered modest benefits, according to two Norwegian trials.
In the NOR-DRUM Part A trial, clinical remission at week 30 was achieved in 50.5% of 198 patients with TDM versus 53% of 200 patients in the standard therapy group, for an adjusted difference of 1.5% (95% CI −8.2% to 11.1%,
P=0.78), reported Silje Watterdal Syversen, MD, PhD, of Diakonhjemmet Hospital in Oslo, and co-authors.
In the ARCTIC REWIND trial, disease flare occurred in 25% of 77 patients in the half-dose conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) group versus 6% in the stable-dose csDMARD group for a risk difference of 18% (95% CI 7% ....

Silje Watterdal Syversen , Novartis Norge , Daiichi Sankyo , Eli Lilly , Infliximab Remicade , Siri Lillegraven , Shalmali Pal , Orion Pharma , Jeffreyr Curtis , Norwegian Regional Health Authorities , Boehringer Ingelheim , Thermo Fisher , University Of Alabama At Birmingham , South Eastern Norway Regional Health Authority , South Eastern Norway Regional Health Authorities , Research Council Of Norway , Diakonhjemmet Hospital , Contributing Writer , Norwegian Regional Health , Galderma Nordic , Bristol Myers Squibb , Merck Sharp , Research Council , South Eastern Norway Regional Health , Eisai Galapagos , தய்ச்சி சாங்கியோ ,

Liver Transplant Emerges for Hepatic Mets in Colorectal Cancer

Norwegian healthcare region has appointed Sectra as enterprise imaging vendor for efficient region-wide patient care


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International medical imaging IT and cybersecurity company Sectra
 (STO: SECT B) has secured an enterprise imaging contract from the South-Eastern Norway Regional Health Authority. The contract comprises a radiology module and a region-wide multimedia solution (VNA) to store medical images and multimedia across all medical specialties. The platform will increase efficiency and collaboration across the region and beyond, translating into improved healthcare for its patients.
We are pleased that we have the agreement in place. The regional solution is strongly needed and will improve the quality of patient care. Clinicians will have faster and easier access to patient information, thus can shorten lead times, comments Cathrine M. Lofthus, CEO, South-Eastern Norway Regional Health Authority (helse-sorost.no). ....

Cathrinem Lofthus , Marie Ekstr , South Eastern Norway Regional Health Authority , Oslo University Hospital , Sectra Imaging It Solutions , South Eastern Norway Regional Health , Eastern Norway Regional Health Authority , Electronic Patient Record , Managing Director Sectra , Nasdaq Stockholm , President Sectra , Executive Vice President Sectra , President Sectra Imaging , தெற்கு கிழக்கு நோர்வே பிராந்திய ஆரோக்கியம் அதிகாரம் , ஒசிலோ பல்கலைக்கழகம் மருத்துவமனை , தெற்கு கிழக்கு நோர்வே பிராந்திய ஆரோக்கியம் , கிழக்கு நோர்வே பிராந்திய ஆரோக்கியம் அதிகாரம் , மின்னணு நோயாளி பதிவு , நாஸ்டாக் ஸ்டாக்‌ஹோல்ம் ,