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Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women


This figure presents serum binding and functional antibody responses following COVID-19 vaccination and SARS-CoV-2 infection among women 45 years or younger.
A and B, Each panel compares vaccine antibody responses at 2 through 8 weeks after the second dose to nonpregnant and pregnant women who were unvaccinated and infected. Thirteen women (7 nonpregnant, 4 pregnant, and 2 lactating) who had baseline samples collected within 7 days of their first vaccine dose were selected based on the earliest sample availability and were analyzed as a negative assay control.
C, D, and E, Systems serology was used to quantify spike-specific antibody–dependent neutrophil phagocytosis (ADNP), antibody–dependent complement deposition (ADCD), and antibody–dependent monocyte cellular phagocytosis (ADCP). ....

United Kingdom , United States , Massachusetts Institute Of Technology , South Africa , Puro Luc Addgene , Apraku Bondzie , Cytofix Cytoperm , Danh Barouch , Glo Luciferase Assay Promega Corp , Burroughs Wellcome Fund , Ragon Institute , Beth Israel Deaconess Medical Center , Harvard Catalyst Clinical Research Center , Melinda Gates Foundation , Ragon Institute Of Massachusetts , Training Program , Reproductive Scientist Development Program , Cellular Technologies Ltd , Graphpad Software , Vaccine Research , Musk Foundation , Translational Science Center , Seromyx Systems Inc , Centers For Disease , Rockland Inc , Department Of Obstetrics ,