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Blood culture surveillance in a secondary care hospital in Benin: epidemiology of bloodstream infection pathogens and antimicrobial resistance | BMC Infectious Diseases

Although global surveillance of antimicrobial resistance (AMR) is considered key in the containment of AMR, data from low- and middle-income countries, especially from sub-Saharan Africa, are scarce. This study describes epidemiology of bloodstream infections and antimicrobial resistance rates in a secondary care hospital in Benin. Blood cultures were sampled, according to predefined indications, in BacT/ALERT FA Plus and PF Plus (bioMérieux, Marcy-l’Etoile, France) blood culture bottles (BCB) in a district hospital (Boko hospital) and to a lesser extent in the University hospital of Parakou. These BCB were incubated for 7 days in a standard incubator and twice daily inspected for visual signs of growth. Isolates retrieved from the BCB were processed locally and later shipped to Belgium for reference identification [matrix-assisted laser desorption/ionization time-of-flight spectrometry (MALDI-TOF)] and antibiotic susceptibility testing (disk diffusion and ....

United States , Waals Gewest , Marcy Letoile , Region Flamande , Saint Jean De Dieu , Baden Wüberg , Coris Bioconcept , Rosco Diagnostica , Bruker Daltonics , Kern Sohn Gmb , Institute Of Tropical Medicine In Antwerp , Microsoft Office , Pro Lab Diagnostics Inc , Rr Foundation For Statistical Computing , Centre Hospitalier Universitaire Departemental , University Hospitals Leuven See Additional , Clinical Laboratory Standards Institute , Boko Hospital , Sohn Gmbh , Laboratory Standards Institute , Tropical Medicine , University Hospitals Leuven , Minimal Inhibitory Concentration , Cleaned Excel , Statistical Computing , For Salmonella Typhi ,

Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany

Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany
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New York , United States , University Hospital , Bitcare Gmb , Centers For Disease , Immunoassay Analyzer Shenzhen Yhlo Biotech Co , University Hospital Munich , Drug Administration , Technical University Of Munich , Laboratory Analysis , University Hospital Munich Rechts Der Isar , R Foundation For Statistical Computing , University Hospital Munich Rechts , Technical University , Appendix Figure , Bitcare Gmbh , Ethics Committee , Munich School , Corona Hotline , Roche Diagnostics , Sample Preparation System , Thermofisher Scientific , Disease Control , Statistical Computing , Appendix Table ,

Frontiers | Genome-Wide Association Analysis Reveals Genetic Loci and Candidate Genes for Chest, Abdominal, and Waist Circumferences in Two Duroc Pig Populations

Chest circumference (CC), abdominal circumference (AC), and waist circumference (WC) are regarded as important indicators for improving economic traits because they can reflect the growth and physiological status in pigs. However, the genetic architecture of CC, AC, and WC is still elusive. Here, we performed single-trait and multi-trait genome-wide association studies (GWASs) for CC, AC, and WC in 2206 American origin Duroc (AOD) and 2082 Canadian origin Duroc (COD) pigs. As a result, one novel quantitative trait locus (QTL) on Sus scrofa chromosome (SSC) 1 was associated with CC and AC in COD pigs, which spans 6.92 Mb (from 170.06 to 176.98 Mb). Moreover, multi-trait GWAS identified 21 significant SNPs associated with the three conformation traits, indicating the multi-trait GWAS is a powerful statistical approach that uncovers pleiotropic locus. Finally, the three candidate genes (ITGA11, TLE3, and GALC) were selected that may play a role in the conformation traits. Further bioinfor ....

Baden Wüberg , United States , New York , Nat Genet , Coheni Pearson , J Clin Nutr , Guangdong Wens Foodstuff Group Co Ltd , Trop Anim Health , Guangdong Wens Breeding Swine Technology Co Ltd , Committee Of The South China Agricultural University , Wens Foodstuffs Group Co Ltd , Life Sciences , Entrepreneurial Research Team Program , R Foundation For Statistical Computing , Geneseek Porcine , Hardy Weinbergp Value , Supplementary Table , Block Analysis , Genetic Parameters , Explained Phenotypic , Explained Phenotypic Variance , Kyoto Encyclopedia , Gene Ontology , Correlation Among , Supplementary Figure , White Duroc ,

Ruling out pulmonary embolism across different healthcare settings: A systematic review and individual patient data meta-analysis

Geert-Jan Geersing and colleagues assess the capability of ruling-out pulmonary embolism by available diagnostic strategies across a range of healthcare settings. ....

United States , Sanjay Basu , Bristol Myers Squibb , Dutch Research Council , International Society On Thrombosis , Harvard Medical School , Principia Biopharma Inc , University Of Ottawa , Stroke Foundation Of Canada , Sanofi Company , Netherlands Organisation For Health Research , Department Of Medicine , Pulmonary Embolism Rule Out Criteria , Geersingg J , Creative Commons Attribution License , Institutional Data Access , Netherlands Organisation , Health Research , Dutch Heart , Venous Thromboembolism , Clinician Scientist , Stroke Foundation , International Society , Preferred Reporting Items , Systematic Reviews , Diagnostic Test Accuracy ,

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial | Critical Care Medicine | JAMA

This randomized clinical trial compares the effect of continuous positive airway pressure or high-flow nasal oxygen vs conventional oxygen therapy on clinical o ....

United Kingdom , Eteläuomen Läi , Brighton And Hove , East Sussex , West Midlands , United Kingdom General , Northern Ireland , City Of , Danielf Mcauley , Eli Lilly , Queen University Belfast , Development Division , Boehringer Ingelheim , Midlands Research Design Service , Wellcome Wolfson Institute For Experimental Medicine , British Heart Foundation , Midlands Applied Research Collaboration , Department Of Health , Care Society , Research Council , Faron Pharmaceuticals , R Foundation For Statistical Computing , Group Information , United Kingdom Research , Sciences Research Council , Health Research Authority ,