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police say a 17-year-old student opening fire just as school was starting in perry, iowa, outside des moines. five students and the principal shot. a sixth grader killed. the others rushed to the hospital. and rachel scott is in iowa for us. the major winter storm targeting new york city and the northeast. heavy snow, rain, potentially damaging winds. at this hour, at least 20 states now under winter alerts. the potential snow totals in new york and the northeast, depending on the track. and rob marciano will show us. the jeffrey epstein case. tonight, the newly unsealed court do...

people limiting outside activity especially for anyone with underlying medical conditions who might have trouble breathing. video from the space station 240 miles up showing the extent of the smoke from wildfires billowing in the atmosphere. the mostly cloudy -- smoke is expected to stick around and the possible danger for many. listen. >> the levels that people if they were to be outside especially if they are exercising breathing faster, they are going to be inhaling particulates at concentrations the normal smokers would inhale. >> dana: dr. saphier joining us in a moment with mor...

marriage to work, i did not give up. >> soon he was gone, vanished without a word or a trace. >> he left the young daughter behind. he left the house. >> was this a husband who did not want to be found? or could this be something else. >> detectives are not an undercover operation. that would lead to a long -- >> hard to say ready for that? i know that it has to happen. >> disappearance in the desert. could it be the perfect crime. i can only imagine what would be like to keep that. welcome to dateline. i'm lester holt. for eight years it was a mystery, a husband who had simply vanis...

welcome, everybody. we begin on the unofficial first day of the summer travel season. and you better pack your patience. 42 million americans will take to the skies this memorial day weekend. experts think it could be one of the busiest on record. now, the white house is pushing to avoid another flight mare like last year. president biden is touting his effort to compensation travelers for flight delays, quote, ledezma up for travelers this memorial day weekend. we launched flight rights.gov. if the flight was cancelled or delayed, check the dashboard to see how you could be compensa...

out front. plus, she is bucking the president again, this time on immigration. but have voters had enough of democrat turned indeputy kyrsten sinema? we are out front in arizona. and new reporting just coming in from cnn's k-file, an up and coming star in the republican party calling survivors of a deadly school shooting spoiled, angry, and stupid. and there is more. let's go "outfront." good evening, i'm pamela brown in for erin burnett. "outfront" tonight, bracing for revenge, the sound of air raid sirens heard across ukraine's capital as the city prepares for russia to retal...