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COVID Moonshot Unveils Crowd-Sourced Covid Antiviral Lead Compound

COVID Moonshot Unveils Crowd-Sourced Covid Antiviral Lead Compound
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Daren Fearon , Gianluigi Botton , Lizbe Koekemoer , Memorial Sloan Kettering Cancer Center , University Of Oxford , Moonshot Consortium , Icahn School Of Medicine At Mount Sinai , Weizmann Institute Of Science , Medchemica Ltd , Nuffield Department Of Medicine , Centre For Medicines Discovery , Enamine Ltd , Neglected Disease , Diamond Light Source , Medicines Discovery , Senior Beamline Scientist , Prof Frank , Principal Beamline Scientist , Structural Chemical Biology , Structure Enabled Antiviral Platform , Nuffield Department , Weizmann Institute , Icahn School , Mount Sinai , Thames Pharma Partners ,

Study helps explain SARS-CoV-2 variants' rapi

The omicron variants of the SARS-CoV-2 virus have rapidly spread around the world over the past year. They latch onto our cells more tightly, invade them more efficiently, and elude many of the antibodies induced by previous infections and vaccines. The human immune system, in turn, tends to respond less effectively by producing antibodies related to previous infections or vaccinations, instead of bespoke antibodies tailored to the newer versions of the coronavirus that causes COVID-19. Findings from this latest study in Nature suggest that vaccine developers make sure vaccines against new variants don't contain components from older variants. These might set off the immune imprinting that can induce a less robust immune response to new variants. ....

Senda Biosciences , Humabs Biomed , Amin Addetia , David Veesler , Michael Mccarthy , Luca Picolli , University Of Washington , University Of Washington School Medicine , Howard Hughes Medical Institute Investigator , Swiss Kidney Foundation , Research Council Of Cantonal Hospital Aarau , Burroughs Wellcome Fund , Us National Institute Of Allergy , Us National Institutes Of Health , Method Of Research , Regeneron Pharmaceuticals , Hyoung Jun Park , Washington School , James Brett Case , Washington University School , Infectious Diseases , Research Council , Cantonal Hospital Aarau , Structure Enabled Antiviral Platform , Vir Biotechnology , Generate Biomedicines ,

Global Collaborators 'cunning plan' for affordable, accessible oral anti-virals - Oct 17 2022 - ASAP - Life Science News Articles

The consortium’s strategy is to create an AI-driven Structure-enabled Antiviral Platform (ASAP), using cutting-edge technology such as advanced structural biology, fragment screening, AI and machine learning, as well as computational chemistry on Folding@home, the world’s largest distributed computing platform to build a robust and open access antiviral discovery pipeline. Click to read more. ....

New York , United States , United Kingdom , Tel Aviv , Tamas Szommer , Daren Fearon , Alpha Lee , Brian Marsden , Oleg Fedorov , Eleanor Williams , Centre For Medicines Discovery , Stanford University School Of Medicine United States , Research Informatics , University Of Oxford , National Institute Of Allergy , Weizmann Institute Of Science Israel , Antiviral Program For Pandemics , Memorial Sloan Kettering Cancer Centre United States , Structural Genomic Consortium , Wellcome Trust , Team Leader , Fred Hutchinson Cancer Center United States , Structure Enabled Antiviral Platform , Palo Alto , Antiviral Drug Discovery , Pandemic Concern ,

Antivirals Discovery Initiative receives NIH Support

“If we had clinic-ready antivirals suitable for SARS-CoV-2 when the pandemic struck in late 2019, we could have perhaps saved millions of lives,” Ben Perry A bid to discover and develop accessible and affordable oral antivirals to combat outbreaks of COVID-19 and future pandemics has received an initial award of $68 million from the US National Institutes of Health (NIH) that will fund the first three-years of a five-year project to produce preclinical candidates against six viral targets. Click to read more. ....

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PostEra spearheads AI-driven drug discovery collaboration to develop antiviral therapeutics with initial $68M in NIH funding – Padovanews

PostEra spearheads AI-driven drug discovery collaboration to develop antiviral therapeutics with initial $68M in NIH funding – Padovanews
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