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SEGRO PLC: SEGRO PLC: RESULTS FOR THE YEAR ENDED 31 DECEMBER 2023

SEGRO PLC: SEGRO PLC: RESULTS FOR THE YEAR ENDED 31 DECEMBER 2023
finanznachrichten.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from finanznachrichten.de Daily Mail and Mail on Sunday newspapers.

United-kingdom , Paris , France-general- , France , London , City-of , Claire-mogford , Soumen-das , David-sleath , Stefan-klotter , Group-annual , Transparency-rules-of-the-financial-conduct-authority

An autonomous laboratory for the accelerated synthesis of novel materials

To close the gap between the rates of computational screening and experimental realization of novel materials1,2, we introduce the A-Lab, an autonomous laboratory for the solid-state synthesis of inorganic powders. This platform uses computations, historical data from the literature, machine learning (ML) and active learning to plan and interpret the outcomes of experiments performed using robotics. Over 17 days of continuous operation, the A-Lab realized 41 novel compounds from a set of 58 targets including a variety of oxides and phosphates that were identified using large-scale ab initio phase-stability data from the Materials Project and Google DeepMind. Synthesis recipes were proposed by natural-language models trained on the literature and optimized using an active-learning approach grounded in thermodynamics. Analysis of the failed syntheses provides direct and actionable suggestions to improve current techniques for materials screening and synthesis design. The high success rate demonstrates the effectiveness of artificial-intelligence-driven platforms for autonomous materials discovery and motivates further integration of computations, historical knowledge and robotics. An autonomous laboratory, the A-Lab, is presented that combines computations, literature data, machine learning and active learning, which discovered and synthesized 41 novel compounds from a set of 58 targets after 17 days of operation.

Supplementary-note , Supplementary-table , Supplementary-notes , Materials-project ,

Central Puerto S A : Relevant part of the Minutes of Central Puerto S.A. Board of Directors' Meeting held on August 11, 2023

Relevant part of the Minutes of Central Puerto S.A. Board of Directors' Meeting held on August 11, 2023

Minutes No. 380:In the City of Buenos Aires, on August 11, 2023, the...
-Today at 11:04 am- MarketScreener

Vuelta-de-obligado , Buenos-aires , Argentina , Distrito-federal , Jorge-eduardo , Manuel-belgrano , Leonardo-marinaro , Statutory-audit-committee , Company-statutory-audit-committee , Board-of-directors-the-company , International-financing-reporting-standards , Nacional-de-valores-argentine-securities-commission

SEGRO PLC: RESULTS FOR THE SIX MONTHS ENDED 30 JUNE 2023

SEGRO PLC: RESULTS FOR THE SIX MONTHS ENDED 30 JUNE 2023
finanznachrichten.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from finanznachrichten.de Daily Mail and Mail on Sunday newspapers.

United-kingdom , Italy , Netherlands , Czech-republic , Granollers , Comunidad-autonoma-de-cataluna , Spain , Greater-london , United-kingdom-general- , France , Midlands , Leicestershire

SEGRO PLC : RESULTS FOR THE SIX MONTHS ENDED 30 JUNE 2023

SEGRO PLC : RESULTS FOR THE SIX MONTHS ENDED 30 JUNE 2023
streetinsider.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from streetinsider.com Daily Mail and Mail on Sunday newspapers.

United-kingdom , Italy , Greater-london , United-kingdom-general- , Berlin , Germany , Luxembourg , Poland , France , Granollers , Comunidad-autonoma-de-cataluna , Spain

Evolutionary histories of breast cancer and related clones

Recent studies have documented frequent evolution of clones carrying common cancer mutations in apparently normal tissues, which are implicated in cancer development1–3. However, our knowledge is still missing with regard to what additional driver events take place in what order, before one or more of these clones in normal tissues ultimately evolve to cancer. Here, using phylogenetic analyses of multiple microdissected samples from both cancer and non-cancer lesions, we show unique evolutionary histories of breast cancers harbouring der(1;16), a common driver alteration found in roughly 20% of breast cancers. The approximate timing of early evolutionary events was estimated from the mutation rate measured in normal epithelial cells. In der(1;16)(+) cancers, the derivative chromosome was acquired from early puberty to late adolescence, followed by the emergence of a common ancestor by the patient’s early 30s, from which both cancer and non-cancer clones evolved. Replacing the pre-existing mammary epithelium in the following years, these clones occupied a large area within the premenopausal breast tissues by the time of cancer diagnosis. Evolution of multiple independent cancer founders from the non-cancer ancestors was common, contributing to intratumour heterogeneity. The number of driver events did not correlate with histology, suggesting the role of local microenvironments and/or epigenetic driver events. A similar evolutionary pattern was also observed in another case evolving from an AKT1-mutated founder. Taken together, our findings provide new insight into how breast cancer evolves. By using phylogenetic analyses of multiple microdissected samples from both cancer and non-cancer lesions, unique evolutionary histories of breast cancers harbouring a common driver alteration are shown, providing new insight into how breast cancer evolves.

Extended-data , Supplementary-notes , Luminala-like , Supplementary-table ,

Project MUSE - Early Latin Theology

Project MUSE - Early Latin Theology
jhu.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from jhu.edu Daily Mail and Mail on Sunday newspapers.

Bernard-lonergan , Early-latin-theology , Supplementary-notes , Sanctifying-grace ,

SEGRO PLC: RESULTS FOR THE YEAR ENDED 31 DECEMBER 2022

SEGRO PLC: RESULTS FOR THE YEAR ENDED 31 DECEMBER 2022
streetinsider.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from streetinsider.com Daily Mail and Mail on Sunday newspapers.

Milan , Lombardia , Italy , Midlands , Leicestershire , United-kingdom , Munich , Bayern , Germany , Paris , France-general- , France

Morris & Luke Quarry, Oak Hill, Westford, Middlesex Co., Massachusetts, USA

Morris & Luke Quarry, Oak Hill, Westford, Middlesex Co., Massachusetts, USA
mindat.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from mindat.org Daily Mail and Mail on Sunday newspapers.

Detailed-mineral-list , Supplementary-notes , Commercial-granites , New-england , Economic-geology ,

Judicial Review Trends and Forecasts 2021 Accountability and Constitution

Introduction The story of our constitution is much like the story of the United Kingdom itself: ‘an everlasting animal stretching into the future and

Finnis , Banbridge , United-kingdom , Northern-ireland , Craigavon , British , Theresa-may , Gerry-adam , Christopher-forsyth , Tom-bingham , David-gauke , R-ekins-ed