Dutch study compares mRNA vaccines to vector-based vaccines for COVID-19
An overview of the PIENTER-Corona (PiCo) study, which is a Dutch nationwide efficacy comparison study on four different COVID-19 vaccines.
Source: news-medical.net
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Frontiers | All-Cause Mortality Risk Associated With Solid Fuel Use Among Chinese Elderly People: A National Retrospective Longitudinal Study
Background The adverse health effects of air pollutants are widely reported, and the elderly are susceptible to toxic environments. This study aimed to identify the all-cause mortality associated with cooking fuel use among the elderly. Methods A total of 5732 and 3869 participants from the Chinese Longitudinal Healthy Longevity Survey were enrolled in two (2014–2018) and three waves (2011–2018) of survey. Cooking fuel was divided into clean and solid fuel. Cox proportional hazards models were used to estimate the mortality hazard ratio (HR). Subgroup analyses were performed to assess the ...
Source: frontiersin.org
Frontiers | Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity
There is a distinct increase in the prevalence of depression with the onset of puberty. The role of peripubertal testosterone levels in boys in this context is insufficiently understood and may be modulated by a functional polymorphism of the androgen receptor gene (AR), a variable number of CAG repeats. Moreover, there is preliminary evidence that the relationship between testosterone, CAG repeat length, and the severity of depressive symptoms may differ between subclinical and overt depression, but this has neither been studied in a clinical sample of adolescents with depression nor compared...
Source: frontiersin.org
Frontiers | Liver Histopathological Analysis of 24 Postmortem Findings of Patients With COVID-19 in China
Although the pathologic investigation of liver injury was observed in a couple of cases in China, the detailed description of liver histopathologic and ultrastructural changes in a relatively larger series of liver tissues from COVID-19 patients is lacking. Samples from the liver were obtained from 24 COVID-19 cases from February 1 to April 1, 2020. Light microscopy showed that all liver sections had different degrees of liver injury manifested as swelling of the hepatocytes, hepatocellular necrosis, steatosis, lobular inflammation, portal inflammation, dilatation of sinusoids, and so on. SARS...
Source: frontiersin.org
Vaccination Coverage by Age 24 Months Among Children Born in 2017 and 2018 — National Immunization Survey-Child, United States, 2018–2020
This report describes vaccine coverage among children during their first 24 months of life.
Source: cdc.gov