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Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors

Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
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United States , Mirati Therapeutics , Supporting Information ,

Spectroscopic Analysis of Concentration Dynamics and Crystallization of Hen Egg-White Lysozyme under Optical Trapping Conditions

Spectroscopic Analysis of Concentration Dynamics and Crystallization of Hen Egg-White Lysozyme under Optical Trapping Conditions
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New York , United States , Polymer Assembly To Amino Acid Crystallization , Molecule Force Spectroscopy , Atomic Force Microscopy , Phase Separation In Supersaturated Lysozyme Solutions , Origami Nanospring That Reveals , Garland Science , Proteinx Ray Crystallography , Valuable Protein , Pharmaceutical Industries , Structural Studies , Protein Self Assembly , Therapeutic Strategies , Comprehensive Medicinal Chemistry , Biotechnological Applications , Single Beam Gradient Force Optical Trap , Optical Trapping , Neutral Particles Using , Optical Tweezers , Methods Primers , Bacterial Flagella Measured , Tissue Mechanics , Nucleic Acids , Optical Tweezers Approaches , Probing Multiscale Protein Mechanics ,

Resilience, innovation and collapse of settlement networks in later Bronze Age Europe: New survey data from the southern Carpathian Basin

Societies of the later Early to Middle Bronze Age (ca. 2200–1600 BC) in the Carpathian Basin exhibited complex, hierarchical and regionally influential socio-political organisation that came to an abrupt end in the 16th century BC. Considered a collapse by some, this change was characterised by abandonment of virtually all central places / nodes in settlement networks. Until recently, the complexity that characterised the period was believed to have substantially diminished alongside depopulation. This model was reinforced by a combination of the loss of established external networks and low-resolution knowledge of where and how people lived in the first stages of the Late Bronze Age (between 1600 and 1200 BC). We contest the idea of a diminished Late Bronze Age and argue that a fully opposite trajectory can be identified–increased scale, complexity and density in settlement systems and intensification of long-distance networks. We present results of a settlement survey in ....

Po Valley , Pannonian Plain , Austria General , Marija Lju , Danilo Jovanovi , Victor Sava , Anthony Harding , Stefanos Gimatzidis , Miroslav Mari , Eleni Gourgouleti , Millan Molloy , Lauren Brown , Neda Mirkovi , Jasna Mir , Jugoslav Pendi , National Museum Service , Serbian Ministry Of Culture , Austrian Academy Of Sciences , European Research Council Consolidator Grant , Middle Bronze Age , Carpathian Basin , Late Bronze Age , Bronze Age Europe , Austrian Academy , Creative Commons Attribution License , Supporting Information ,

Flexible Robust Optimization Planning of Wastewater–Energy Nexus-Based Biofuel Network Design under Cultivation Rate and Climate Change Uncertainty

Flexible Robust Optimization Planning of Wastewater–Energy Nexus-Based Biofuel Network Design under Cultivation Rate and Climate Change Uncertainty
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United States , World Water Development Report Volume , Renewable Energy , J Energy Res , Us Department Of Energy , Renewable Sustainable Energy Rev , J Energy Sect , Energy Grids Netw , Energy Biosci , Agriculture Organization Of The United Nations , Battelle Geneva Research Center , Sms National , Sustainable Energy , Supply Chain , World Water Assessment , Managing Water , Supply Chain Management , South Western Cengage Learning , Coffee Cut Stem , Midwestern United , Land Use Policy , Energy Grids , Agriculture Organization , United Nations , Supporting Information ,

What is the best pathway to nursing in the UK?

In this article, we’ll outline the role SIFE and OET play in helping you achieve your dreams of living and working in the UK. ....

United Kingdom , Midwifery Council , Supporting Information , United Kingdom Employer , Objective Structured Clinical Examination , Care Worker ,