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College of Human Medicine professor and collaborators named Inventors of the Year

College of Human Medicine professor André Bachmann and two Corewell Health physicians, Caleb Bupp and Surender Rajasekaran, have been named the 2023 Inventors of the Year for their discovery of a previously unknown disease and development of an effective treatment.

New-york , United-states , Caleb-bupp , Surender-rajasekaran , Teresa-woodruff , National-institutes-of-health , College-of-human-medicine , Johns-hopkins-university-school-of-medicine , York-intellectual-property-law-association , Corewell-health , Department-of-pediatrics , International-center

Orbus Therapeutics Enters Exclusive License Agreement for

Eflornithine method for use patent from Michigan State University/Corewell Health® relates to treating patients with rare Bachmann-Bupp Syndrome...

Anupam-jhingran , Bob-myers , Kelli-perkins , Caleb-bupp , Jason-levin , Surender-rajasekaran , Corewell-health , Orbus-therapeutics-inc , Michigan-state-university , European-medicines-agency , Drug-administration , Committee-for-medicinal-products-human-use

Spectrum, MSU find COVID-19 patients fall into two groups - Grand Rapids Business Journal

A new study could lead to greater understanding of COVID-19 treatment after underscoring the importance of precision medicine and personalized care.

Jeremy-prokop , Surender-rajasekaran , Rapids-community-college , Michigan-state-university , National-institutes-of-health , Calvin-university , Michigan-state-university-college-of-human-medicine , Michigan-state-university-alliance , Valley-state-university , Davenport-university , Spectrum-health-foundation-gala

Doctors Treat Girl's Genetic Disorder with Repurposed Drug

In just 16 months, physicians went from identifying a novel rare disease in three-year-old Marley to successfully treating her with a drug previously used to treat African sleeping sickness and pediatric cancer.

Michigan-state-university , Michigan , United-states , Kwame-anyane-yeboa , Anne-pariser , Johns-hopkins , Tracy-murray-stewart , Kelly-berthoud , Caleb-bupp , Surender-rajasekaran , National-institutes-of-health , Office-of-rare-diseases-research

2 years into treatment, girl with new genetic disorder much improved

2 years into treatment, girl with new genetic disorder much improved
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Michigan-state-university , Michigan , United-states , California , Mark-johnson-lansing , Helen-devos , Kelly-berthoud , Caleb-bupp , Surender-rajasekaran , Human-development , National-institutes-of-health , Drug-administration

Marley's marvelous success | MSUToday | Michigan State University

Marley’s marvelous success
New rare genetic syndrome goes from a collection of symptoms to successful treatment in less than two years
Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient — in this case a child — and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.
The paper chronicling this lightning-fast scientific response to Bachmann-Bupp Syndrome was published on July 13 in the open-access journal, eLife.
Andre Bachmann
For more than 25 years, André Bachmann, professor of pediatrics in Michigan State University College of Human Medicine, had been studying the ODC1 gene. This gene and its protein product ODC, which produce polyamines, are crucial for cell survival and contribute to many developmental processes, including muscle tone and motor skills in children.

Morrisville , North-carolina , United-states , Helen-devos , Marley-berthoud , Andre-bachmann , Caleb-bupp , Surender-rajasekaran , Human-development , Michigan-state-university-college-of-human-medicine , Drug-administration , Department-of-pediatrics

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months

Child with Bachmann-Bupp Syndrome successfully treated in just 16 months
Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.
The paper chronicling this lightning-fast scientific response to the Bachmann-Bupp Syndrome was published in the open-access journal,
eLife.
For more than 25 years, André Bachmann, professor of pediatrics in Michigan State University College of Human Medicine, had been studying the ODC1 gene. This gene and its protein product ODC, which produces polyamines are crucial for cell survival and contribute to many developmental processes, including muscle tone and motor skills in children.

Morrisville , North-carolina , United-states , Helen-devos , Marley-berthoud , Caleb-bupp , Emily-henderson , Surender-rajasekaran , Human-development , Michigan-state-university-college-of-human-medicine , Drug-administration , Department-of-pediatrics

Child with rare genetic syndrome successfully treated in less than two years

Child with rare genetic syndrome successfully treated in less than two years
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Michigan-state-university , Michigan , United-states , Morrisville , North-carolina , Grand-rapids , Marley-berthoud , Helen-devos , Caleb-bupp , Surender-rajasekaran , Human-development , Michigan-state-university-college-of-human-medicine

Black Impact Collaborative explains vaccine distrust among African Americans

Black Impact Collaborative explains vaccine distrust among African Americans
Hesitancy in community dates back decades
The Black Impact Collaborative held a community conversation Wednesday.
and last updated 2020-12-10 00:34:31-05
GRAND RAPIDS, Mich. â The Black Impact Collaborative held a community conversation on Wednesday over Zoom, speaking about clinical trials and vaccines and the hesitancy among the African American community with them.
The forum host and BIC member, Dr. Walter Brame, explained that âit is crucial to share this information so that everyone is empowered to make confident and informed decisions,â about whether to take a COVID 19 vaccine once it is offered.

United-states , Americans , American , Walter-brame , Surender-rajasekaran , Research-at-spectrum-health , Tuskegee-institute , Malaria-research , Black-impact-collaborative , African-american , Medical-director , Spectrum-health