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Blow to Roche's cancer immunotherapy prospects as second trial fails

Development of a new cancer immunotherapy pioneered by Roche was thrown in doubt on Wednesday when its drug tiragolumab failed to slow the progression of lung cancer in a second trial. ....

Junshi Biosciences , Bristol Myers Squibb , Teos Therapeutics Inc , Gilead Sciences , Merck Co , Agenus Inc , Arcus Biosciences , Myers Squibb , Shanghai Junshi Biosciences , Cancer Immunotherapy Prospects , Anti Tigit , Merck Amp Co , Coherus Biosciences , Agenus Inc 39 S , Ludwig Burger , John Revill , Tom Hogue , Iteos Therapeutics Inc 39 S , Reaking News , Sunday Times , He Times , Usiness Times , Shisa Live ,

Roche posted a big Q1 sales gain. So why is the company expecting a slowdown later this year?

Roche delivered a double-digit sales increase in the first quarter, but CEO Severin Schwan still thinks the company’s full-year haul may come in flat versus 2021. ....

Covid 19 , Quarterly Sales , Drug Sales , Fierce Pharma Homepage ,

F. Hoffmann-La Roche Ltd: CHMP recommends EU approval of Roche's Tecentriq as adjuvant treatment for a subset of people with early-stage non-small cell lung cancer

In the Phase III IMpower010 trial, adjuvant Tecentriq reduced the risk of disease recurrence or death by 57% in people with PD-L1 high resectable Stage II-III NSCLC compared with best supportive careMore ....

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After trial flop, Exelixis drops plan to pair Cabometyx with Roche's Tecentriq in early-stage liver cancer

After last year’s surprise flop in previously untreated hepatocellular carcinoma (HCC) the most common type of liver cancer Exelixis’ hopes dimmed around the combination of its tyrosine kinase inhi ....

Combination Therapy , Immuno Oncology , Liver Cancer , Clinical Data , Fierce Pharma Homepage ,

F. Hoffmann-La Roche Ltd: New data from the phase II CITYSCAPE trial show encouraging results with Roche's novel anti-TIGIT tiragolumab plus Tecentriq

After 2.5 years median follow-up, pre-planned exploratory analyses in the PD-L1-high population show clinically meaningful results, with overall survival not yet reached and continued progression-free ....

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