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Low blood concentrations of glucose (hypoglycaemia) soon after birth are common because of the delayed metabolic transition from maternal to endogenous neonatal sources of glucose. Because glucose is the main energy source for the brain, severe hypoglycaemia can cause neuroglycopenia (inadequate supply of glucose to the brain) and, if severe, permanent brain injury. Routine screening of infants at risk and treatment when hypoglycaemia is detected are therefore widely recommended. Robust evidence to support most aspects of management is lacking, however, including the appropriate threshold for ...

Newborns at risk of brain damage from low blood sugar levels are increasingly safe, as research at the University of Auckland’s Liggins Institute continues to break new ground, with two papers published in the same edition of the prestigious Journal

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Two papers in the same edition of JAMA plus an editorial recognises importance of Liggins research into newborns with hypoglycaemia

Conflicting research on downstream effects of low blood sugar in newborns