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T Cells Engineered To Attack a Variety of Cancers


 
Control mice (left panel) with prostate cancer show large areas of metastasis in the lungs (blue). When a subset of animals were treated with unmodified T cells (middle panel), the secondary tumors were smaller than in untreated mice. And when a separate group of mice received T cells engineered to produce MDA-7/IL-24 (right panel), metastases shrunk even more, in some cases down to nothing. Credit: Shawn Wang, PhD
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Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow s print edition of Cancer Research. ....

Xiang Yang Shawn Wang , Thelma Newmeyer Corman , Paulb Fisher , Cancer Research , Virginia Commonwealth University Massey Cancer Center , School Of Medicine , National Cancer Institute , Institute Of Molecular Medicine , Department Of Human , Oncology Research , Cancer Biology , Developmental Therapeutics , Molecular Genetics , Molecular Medicine , Thelma Newmeyer Corman Endowed Chair , Judy Wason Distinguished Professorship , புற்றுநோய் ஆராய்ச்சி , வர்ஜீனியா காமன்வெல்த் பல்கலைக்கழகம் மஸ்ஸி புற்றுநோய் மையம் , பள்ளி ஆஃப் மருந்து , தேசிய புற்றுநோய் நிறுவனம் , நிறுவனம் ஆஃப் மூலக்கூறு மருந்து , துறை ஆஃப் மனிதன் , புற்றுநோயியல் ஆராய்ச்சி , புற்றுநோய் உயிரியல் , வளர்ச்சி சிகிச்சை , மூலக்கூறு ஜெநெடிக்ஸ் ,